Total pleural coverage followed by lung transplantation in patient with lymphangioleiomyomatosis
AbstractTuberous sclerosis complex lymphangioleiomyomatosis (TSC-LAM) is a rare disease, which may develop an intractable pneumothorax. Chemical or mechanical pleurodesis is a general management to prevent recurrence of pneumothorax, rendering it difficult to later dissect the pleura and control intraoperative bleeding. Since total pleural coverage (TPC) alternative to pleurodesis has been firstly reported by Kurihara et al. (Jpn J Thorac Cardiovasc Surg 54:274,2006), TPC was performed in case of a 46-year-old female with a secondary spontaneous pneumothorax caused by TSC-LAM and followed by lung transplantation. Final pathological report showed the reinforced visceral pleura in the absence of dense adhesions.
Abstract The transplantation of neural stem cells (NSCs) has become an emerging treatment for neural degeneration. A key factor in such treatments is to manipulate NSC behaviors such as proliferation and differentiation, resulting in the eventual regulation of NSC fate. Novel bionanomaterials have shown usefulness in guiding the proliferation and differentiation of NSCs due to the materials' unique morphological and topological properties. Among the nanomaterials, graphene has drawn increasing attention for neural regeneration applications based on the material's excellent physicochemical properties, surface modif...
A highly engineered anti-CD20 antibody, obinutuzumab, enhances renal responses in lupus nephritis compared with standard immunotherapy and is well tolerated. A Phase 3 study is planned for 2020.Medscape Medical News
AbstractPurposeThis prospective cohort study of Japanese university students aimed to identify factors that might affect oral health-related quality of life (OHRQoL) and longitudinal relationships over a period of 3 years.MethodsStudents (n = 487) provided complete data before entering and 3 years later (before university graduation) participated in the present study. Decayed, missing, and filled teeth (DMFT) scores, community periodontal index, ratios (%) of teeth with bleeding on probing, and malocclusion were determined during o ral examinations. The questionnaire addressed age, sex, self-rated oral...
The surgical director of the heart transplant program at Cincinnati Children ’s Hospital has been hired by another leading pediatric hospital.
Conditions: Hematologic Diseases; Chronic Myeloid Leukemia; Acute Myeloid Leukemia; Acute Lymphoid Leukemia; Myelodysplastic Syndromes; Non Hodgkin Lymphoma; Stem Cell Transplant Complications; Chronic Lymphocytic Leukemia Intervention: Other: No intervention Sponsor: Rigshospitalet, Denmark Not yet recruiting
Condition: Graft Versus Host Disease (GVHD) Interventions: Biological: Alpha-1 antitrypsin (AAT); Drug: Placebo Sponsors: CSL Behring; Blood and Marrow Transplant Clinical Trials Network; National Institutes of Health (NIH); National Heart, Lung, and Blood Institute (NHLBI); National Cancer Institute (NCI) Not yet recruiting
Condition: Hepatocellular Carcinoma Interventions: Drug: Lenvatinib; Drug: Placebo; Drug: Immunosuppressive regimen Sponsor: RenJi Hospital Not yet recruiting
Conditions: Intraoperative Bleeding; Postoperative Delirium Interventions: Drug: Bupivacaine 0.5% Preservative-Free Injectable Solution; Drug: normal saline Sponsors: Assiut University; saeid metwaly abouelyazid elsawy Recruiting
Condition: Acute Myeloid Leukemia Interventions: Drug: Glasdegib; Drug: Gemtuzumab Ozogamicin Sponsor: Gruppo Italiano Malattie EMatologiche dell'Adulto Not yet recruiting
CONCLUSION: We concluded that there are three types of extravasation mucocele dermoscopically and clinically and these types may be stages of transition between each other. PMID: 31731335 [PubMed - as supplied by publisher]