Statins and gastroesophageal reflux disease: A meta-analysis

Conclusions: The current meta-analysis found that the risk of GERD was numerically lower among statin users although the pooled result did not reach statistical significance. Therefore, more studies are still needed to further clarify this potential benefit of statins.
Source: Journal of Postgraduate Medicine - Category: Internal Medicine Authors: Source Type: research

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This study was aimed at assessing the role of H. pylori infection in GERD utilizing a large cohort of patients diagnosed with GERD. Methods and Materials: All patients who underwent gastroscopy for an indication of GERD during the study period between 2015 and 2017 at the EMMS Nazareth Hospital were considered eligible for the study and therefore were included. H. pylori infection was determined by the rapid urease test or histology. Severity of esophagitis was assessed using the Los Angeles classification. Univariate analysis was performed to figure out differences between patients according to H. pylori infection sta...
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
While the primary risk factor for oesophageal adenocarcinoma (OAC) and its precursor lesion Barrett ’s oesophagus (BO) is gastro-oesophageal reflux, the infection withHelicobacter pylori (H. pylori) is the dominant risk factor for gastric cancer. Reduction of reflux by dietary measures and proton pump inhibitors has some merits in OAC prevention, and the chemopreventive effect of Aspirin and statins is being widely investigated; however, improved outcome in OAC occurs primarily as the result of secondary prevention. Early detection of neoplastic lesions in Barrett ’s metaplasia can be achieved by surveillance e...
Source: Digestive Diseases - Category: Gastroenterology Source Type: research
Authors: Khoury T, Mari A, Amara H, Jabaren M, Watad A, Nseir W, Sbeit W, Mahamid M Abstract Background and Aims: We aimed to assess whether chronic statins used (> 6 months) were protective of the development of esophagitis in patients with gastroesophageal reflux disease. In the presence of esophagitis, complications such as strictures, Barrett's esophagus, and adenocarcinoma were the most common. Statins, lipid lowering drugs with a pleiotropic effect, are recently implicated in various pathologies. Nevertheless, the possible impact of statins in esophagitis development has never been assessed. Methods: W...
Source: Canadian Journal of Gastroenterology - Category: Gastroenterology Tags: Can J Gastroenterol Hepatol Source Type: research
Take a look at the list of medications people have been able to stop by following the Wheat Belly lifestyle. These represent medications prescribed by doctors to, in effect, “treat” the consequences of consuming wheat and grains. They prescribe drugs to treat inflammation, swelling, skin rashes, gastrointestinal irritation, high blood sugars, airway allergy, joint pain, high blood pressure, leg edema and other abnormal effects caused by wheat and grains. The list includes anti-inflammatory and pain medication, acid reflux drugs, injectable and oral drugs for diabetes, numerous anti-hypertensive agents, asthma i...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates autoimmune blood sugar bowel flora cholesterol Gliadin gluten-free grain-free grains Inflammation undoctored Weight Loss wheat belly Source Type: blogs
Health, weight, and appearance are transformed by living the Wheat Belly lifestyle. You can see it on the face with reduced puffiness and edema and smoother skin. You can see it on the waistline as inflammatory visceral fat recedes. You can perceive it as increased energy, reduced depression and anxiety, reduction or elimination of irritable bowel syndrome and acid reflux symptoms, reduced joint pain, reversal of leg/ankle edema, and in so many other ways. But how about blood measures of health? You can witness the transformations there, too. And the transformations you see in blood markers of health can be just as dramati...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates cholesterol Inflammation triglycerides Weight Loss wheat belly Source Type: blogs
I was recently invited to speak at David Wolfe’s Longevity NOW conference in Anaheim, California, where I gave a talk entitled “Germs, Muscle, and Pac-Man: New Strategies for Turning the Clock Back 10 or 20 Years” detailing some new strategies for maintaining youthfulness and vigor. (It was a longevity conference, after all. I shall be posting a similar talk on our Undoctored Inner Circle website in the next few days.) Of the 40-some vendor booths that were part of the conference, there was one that caught my eye: O’NA HealthCare. They claim to provide coverage for functional medicine care, integrat...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Undoctored Wheat Belly Lifestyle health insurance healthcare low-cost Source Type: blogs
This article reviews this relationship and provides recommendations for management. Keywords: Insomnia, sleep disorder, psychiatric disorder, depression, psychosis, schizophrenia, anxiety disorder Insomnia affects 25 million people in the United States annually and leads to an estimated $100 billion health care burden. Insomnia has also been shown to be a causal factor in other medical and psychiatric disorders, cognitive impairments, accidents, absenteeism, and reduced quality of life.1 The cost of not treating insomnia is more than the cost of treating insomnia.2 Insomnia as a symptom is seen in up to one third of the Un...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Review anxiety disorder depression insomnia psychiatric disorder psychosis schizophrenia sleep disorder Source Type: research
I hear this comment with some regularity when, for instance, someone recognizes me as the author of the Wheat Belly series. This is a step in the right direction. But saying that you have a wheat intolerance is like saying “I have a tobacco intolerance.” The impact of tobacco smoking on health ranges from mild impairment, to incapacitating diseases such as chronic lung disease and abdominal aortic aneurysms, to death. A rare person escapes the ravages of years of smoking, but most people develop at least one, if not half-a-dozen, health problems from cigarettes. And so it goes with wheat: It’s a rare pers...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Wheat Belly Lifestyle gluten gluten-free grain grain-free grains health Inflammation Source Type: blogs
Here’s a sample of the recent Amazon reviews for my book, Undoctored: Why Health Care Has Failed You and How You Can Become Smarter Than Your Doctor. I am encouraged by the overwhelmingly positive feedback, as we are in a virtual war with Big Pharma, the medical device industry, and the hospital industry, all working around-the-clock to take more money out of your pocket while denying you real health. The powerful and pervasive campaign of misinformation conducted by many people in healthcare is impossible to ignore. Getting the Undoctored message out to the public is more important than ever before. The real tragedy...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Undoctored Wheat Belly Lifestyle autoimmune blood sugar bowel flora cholesterol diabetes diy health Dr. Davis grain-free healthcare Inflammation Source Type: blogs
Let’s take back control over personal health. Share this to expose healthcare for the corrupt enterprise it is. Imagine that you receive a letter in the mail stating “In order to retain your right to freedom of speech, you will be billed $10,000 per year every year for the rest of your life.” You would be—-understandably-—outraged. Freedom of speech in America is precious, something Americans have waged wars to defend, something we now view as a basic right, no financial price required to maintain it. It should be free and available to everyone regardless of religion, color, political leanin...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Undoctored Wheat Belly Lifestyle diy health Dr. Davis grain-free healthcare Source Type: blogs
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