Organ sparing of linac-based targeted marrow irradiation over total body irradiation.

CONCLUSION: TMI is capable of maintaining CTV coverage as compared to that achieved in TBI, while significantly sparing organs at risk. Improvement on sparing organs at risk permits a higher prescribed dose to the target or the maximum number of times marrow conditioning may be delivered to a patient while maintaining similar typical tissue complication rates.
PMID: 31605462 [PubMed - as supplied by publisher]

Source: Journal of Applied Clinical Medical Physics - October 10, 2019 Category: Physics Authors: Warrell GR, Colussi VC, Swanson WL, Caimi PF, Mansur DB, de Lima MJG, Pereira GC Tags: J Appl Clin Med Phys Source Type: research