The future of robotics: in a transhuman world, the disabled will be the ones without prosthetic limbs
Bertolt Meyer's amazing bionic hand controlled by an iPhone app is a glimpse of the advances being made in prosthetics. But in years to come, will everyone want one?Bertolt Meyer is used to being viewed as not fully human. Born with a stump where his left hand should have been, he spent his childhood wearing a hook connected to an elaborate pulley and harness. "To open the hook and grasp things I had to flex my shoulders like this," he says, striking a he-man pose. "The harness was very uncomfortable. To stop it chafing my skin, I had to wear a shirt underneath it at all times. I was always sweating."Even when, at the age of 19, Meyer exchanged his body-powered hook for a myoelectric prosthesis with a more realistic plastic hand, he kept his disfigured left arm hidden from view. "It wasn't simply a question of aesthetics," he explains, proffering the plastic hand, now grubby and discoloured with use. "You have to understand, this is a stigma. People think it's weird and that is how you come to perceive it. You walk around with a sense of shame."Today, that shame is gone. In 2009 Meyer, a social psychologist at the University of Zurich, was fitted with an i-limb, a state-of-the-art bionic prosthesis developed by a Scottish company, Touch Bionics, that comes with an aluminium chassis and 24 different grip patterns. To select a new suite of gestures, Meyer simply taps an app on his iPhone."This is the first prosthesis where the aesthe...
ConclusionThis study demonstrated that intravenous dexmedetomidine during hernia repair with local anesthesia is safe and the results were satisfactory to both operators and patients.
ConclusionThe presented missions contribute significantly to an improvement in local healthcare and decrease the burden of disease. We were able to show the sustainable character of these surgical missions. As a next step, we will analyse the cost-effectiveness of MSTs.
We report the case of a patient with Steinert disease showing an early onset ventricular dysfunction due to chronic right ventricular apical pacing, in which an epicardial left ventricular lead implantation was performed following the failure of the percutaneous attempt. As no relief in symptoms of heart failure, nor an improvement of left ventricular ejection fraction and reverse remodelling was observed six months later, the patient was addressed to the heart transplantation. PMID: 29770365 [PubMed - in process]
Conclusions: In this review we will provide animal and human research data on the current clinical neurological uses for CBD individually and in combination with Δ9-THC. We will emphasize the neuroprotective, antiinflammatory, and immunomodulatory benefits of phytocannabinoids and their applications in various clinical syndromes. PMID: 29770251 [PubMed]
(MedPage Today) -- This week's topics include the Ebola vaccine, stroke risk and resolved a-fib, an antibody for migraine prevention, and cannabis and tobacco smoking by parents
Authors: Baird JF, Sandroff BM, Motl RW Abstract INTRODUCTION: Mobility disability is one of the most widespread and impactful consequences of multiple sclerosis (MS). Disease modifying drugs (DMDs) may delay the progression of disability over time; however, there is minimal evidence supporting the efficacy of DMDs for reversing mobility disability or restoring ambulatory function in persons with MS. Areas covered: This review outlines symptomatic pharmacologic and non-pharmacologic therapeutic approaches that target mobility disability with the goal of restoring and improving walking function. First, the efficacy of ...
CONCLUSION: The present review elucidates the effect of IR on various oncogenic RTKs and their mechanisms, downstream signaling, intracellular translocations, their role in the repair of radiation-induced DNA damage and post-irradiation survival. Based on the knowledge derived from RTK biology and the analysis of relevant clinical trials, this review attempts to identify radiobiological considerations, which could be implemented in future trials, combining radiotherapy with RTK-antagonist. Additionally, we identify the radiosensitizing potential of recently-developed RTK-targeted nanoformulations. This review would probabl...
Authors: Seong KM, Kwon T, Park J, Youn B, Cha HJ, Kim Y, Moon C, Lee SS, Jin YW Abstract PURPOSE: Since the 2011 Fukushima nuclear power plant accident, Korean radiation experts have agreed that reliable data on health risks of low-dose radiation (LDR) are needed to ease the anxiety of lay people. The intent of this study was to devise a sustainable biological program suited for the research environment in Korea and aimed at the health effects of radiation exposures
In this study we generate hematopoietic-restricted models of Ptpn11E76K-mediated disease using Csf1r-MCM and Flt3Cre. We show that these animals have indolent MPN progression despite robust GM-CSF hypersensitivity and Ras-Erk hyperactivation. Rather, the dominant pathology is pronounced thrombocytopenia with expanded extramedullary hematopoiesis. Furthermore, we demonstrate that the timing of tamoxifen administration in Csf1r-MCM mice can specifically induce recombinase activity in either fetal or adult hematopoietic progenitors. We take advantage of this technique to show more rapid monocytosis following Ptpn11E76K expres...
Authors: Saner FH, Bezinover D PMID: 29774730 [PubMed - as supplied by publisher]
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