Genetic and environmental influences on corticostriatal circuits in twins with autism

Conclusion: Genetic factors primarily contribute to structural variation in subcortical CSC regions, regardless of ASD, but environmental factors may exert a greater influence on the development of grey matter thickness in the OFC and ACC in children with ASD. The increased vulnerability of OFC grey matter to environmental influences may also mediate some heterogeneity in RRB severity in children with ASD. PMID: 31603639 [PubMed - as supplied by publisher]
Source: Journal of Psychiatry and Neuroscience - Category: Psychiatry Tags: J Psychiatry Neurosci Source Type: research

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Abstract We used an online survey to gather perspectives of autistic youth (n = 248) on the impacts of autism, school professionals, family members, and peers on their high school experiences; what each stakeholder group could have done better; and what future high school professionals and autistic youth should know. Two-thirds of participants viewed autism as negatively impacting their school experience, and this was more prevalent in women. The majority viewed impacts of school professionals, family, and peers as positive. Women were more likely to view school professional contributions as positive...
Source: Journal of Autism and Developmental Disorders - Category: Psychiatry Authors: Tags: J Autism Dev Disord Source Type: research
ConclusionsAll patients with severe autism had SPAs. However, they did not correlate with FDG-PET findings.
Source: Indian Journal of Pediatrics - Category: Pediatrics Source Type: research
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Brain scans of autistic and non-autistic men reveal an association between white matter aberrations and the ages of their fathers at the time the sons were born.
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Condition:   Autism Spectrum Disorder Intervention:   Diagnostic Test: Anatomical MRI Scan Sponsor:   San Diego State University Active, not recruiting
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