Co-Infection of Scrub Typhus and Human Granulocytic Anaplasmosis in Korea, 2006.

CONCLUSION: We found retrospective molecular evidence of the co-infection of scrub typhus and HGA in Korea. HGA may be more prevalent than expected and need to be considered as an important differential diagnosis of febrile patients in Korea. PMID: 31602827 [PubMed - in process]
Source: Journal of Korean Medical Science - Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

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ConclusionsOur findings indicated thatA.phagocytophilum infection was prevalent but unrecognized in Taiwan.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Publication date: Available online 28 November 2018Source: IDCasesAuthor(s): Kelsey Uminski, Kamran Kadkhoda, Brett L Houston, Alison Lopez, Lauren J. MacKenzie, Robbin Lindsay, Andrew Walkty, John Embil, Ryan ZarychanskiAbstractHuman Granulocytic Anaplasmosis (HGA) is an infection caused by the intracellular bacterium Anaplasma phagocytophilum. As a tick-borne disease, the public health impact of HGA continues to increase with range expansion of the disease vector. The clinical presentation of HGA is often a non-specific febrile illness. The presence of leukopenia, thrombocytopenia, and mild hepatic injury are frequently ...
Source: IDCases - Category: Infectious Diseases Source Type: research
Publication date: Available online 24 July 2018Source: Microbial PathogenesisAuthor(s): M. Azmat, M. Ijaz, S.H. Farooqi, A. Ghaffar, A. Ali, A. Masud, S. Saleem, A. Rehman, M.M. Ali, K. Mehmood, Amjad Khan, H. ZahngAbstractCamel Anaplasmosis is caused by members of family Anaplasmatacae, a tick transmitted, obligate intracellular bacteria. The etiological bacteria are transmitted by ixodid tick species. The species have multi host range distribution that is why it is crucial to diagnose it timely. The aim of present study was to investigate the molecular epidemiology i.e. prevalence and risk factors analysis of camel anapl...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Abstract Two dogs from Quebec were diagnosed with granulocytic anaplasmosis. They both displayed fever, lethargy, and anorexia. Other clinical signs included vomiting, uveitis, polyarthritis, hepatomegaly, and splenomegaly. Thrombocytopenia, anemia, and lymphopenia were identified in both cases. Cytoplasmic inclusions were observed within neutrophils, and Anaplasma phagocytophilum infection was confirmed by polymerase chain reaction in both dogs. PMID: 29910483 [PubMed - in process]
Source: The Canadian Veterinary Journal - Category: Veterinary Research Authors: Tags: Can Vet J Source Type: research
ObjectivesTo describe the clinical signs, laboratory results, therapy and course of disease in dogs with canine granulocytic anaplasmosis in which co‐infections had been excluded. MethodsMedical records of dogs naturally infected with Anaplasma phagocytophilum were retrospectively evaluated with regard to clinical signs and laboratory abnormalities at the time of presentation, therapy and course of disease. ResultsNine hundred and seventy‐four dogs with clinical signs suspicious for canine granulocytic anaplasmosis were tested for A. phagocytophilum DNA by modified real‐time PCR; 72 dogs had a positive result. Nine o...
Source: The Journal of Small Animal Practice - Category: Veterinary Research Authors: Tags: PAPER Source Type: research
Human granulocytic anaplasmosis (HGA) is a tick-borne infection, caused by the obligate intracellular bacterium, Anaplasma phagocytophilum, which infects human neutrophils. HGA may be manifested as an acute and sometimes severe febrile summertime illness frequently associated with leukopenia and thrombocytopenia. The vectors of HGA are certain Ixodes species ticks, including Ixodes scapularis (also called the black-legged or deer tick which is found in the northeast and northcentral United States), Ixodes pacificus (the western black-legged tick which is found in the western United States) and Ixodes ricinus (the sheep tic...
Source: Diagnostic Microbiology and Infectious Disease - Category: Microbiology Authors: Source Type: research
Abstract Human granulocytic anaplasmosis (HGA) is a tick-borne rickettsial zoonosis with fever, thrombocytopenia, and leukopenia. HGA has been reported in Korea in 2013 but it is uncertain how long it has existed. A retrospective study was conducted on patients who underwent bone marrow examination due to fever and cytopenia, with no clear hematologic or microbiologic causes, from 2003 through 2012. Laboratory diagnosis was made by detecting 16S rRNA genes of Anaplasma phagocytophilum from the stored blood samples. Among the 70 patients, five (7.1%) HGA cases were found, and the earliest case dated back to 2006. T...
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
Publication date: Available online 2 March 2016 Source:Ticks and Tick-borne Diseases Author(s): Handan Çetinkaya, Erdal Matur, İbrahim Akyazi, Elif Ergul Ekiz, Levent Aydin, Mufit Toparlak In recent years, tick-borne diseases like ehrlichiosis and anaplasmosis became widespread worldwide threatening the health of both human and companion animals. Therefore, the aim of this study was to determine the presence of Anaplasma spp., and Ehrlichia spp. in dogs and ticks in the Thrace Region of Turkey. A total of 400 blood samples and 912 ticks were collected from dogs living in shelters that are located in four ci...
Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
Publication date: Available online 25 January 2016 Source:IDCases Author(s): Joseph DeRose Human Granulocytic Anaplasmosis is a traditionally tick borne illness characterized by non-specific symptoms. 63 year old man with medical history of HIV on ART, presented to EO-VAMC with a complaint of cyclic fevers, chills, and diarrhea. Symptoms began with generalized weakness one week prior to presentation. Patient revealed he was a hunter and experienced trauma to his hand while butchering a deer. He denied vomiting, hematemesis, sick contacts, changes in diet, shortness of breath, recent travel or known tick exposure. Patien...
Source: IDCases - Category: Infectious Diseases Source Type: research
Publication date: Available online 30 September 2015 Source:Microbes and Infection Author(s): Stanka Lotrič-Furlan, Tereza Rojko, Mateja Jelovšek, Miroslav Petrovec, Tatjana Avšič-Županc, Lara Lusa, Franc Strle To assess the value of clinical definitions for human granulocytic anaplasmosis (HGA) epidemiological, clinical and laboratory findings in 50 adult patients with proven HGA (Anaplasma phagocytophilum isolated from blood, and/or positive PCR result, and/or seroconversion or ≥4−fold change in serum IFA antibody titres to A. phagocytophilum) and 46 patients with probable HGA (demonstr...
Source: Microbes and Infection - Category: Infectious Diseases Source Type: research
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