Evaluation of immunogenicity and protective effect of DNA vaccine encoding surface antigen1 (SAG1) of Toxoplasma gondii and TLR-5 ligand as a genetic adjuvant against acute toxoplasmosis in BALB/c mice

ConclusionThis investigation indicated that cocktail DNA vaccine encoded SAG1 gene of T. gondii and FliC can protect against acute toxoplasmosis.
Source: Biologicals - Category: Biology Source Type: research

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Publication date: November 2020Source: Fish &Shellfish Immunology, Volume 106Author(s): Max J. Beckmann, Marcia Saraiva, Debbie McLaggan, Tom G. Pottinger, Pieter van West
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
WHO warns death tollcould be higher than 2 million without concerted action;Madrid braces for lockdown as Spain reaches 716,481 total infections;surge in cases in AthensFigures prompt French and Dutch warnings, and row in SpainUS approaches 7m cases as officials warn surge could comeWhat lessons can Europe learn from Sweden ’s experience?Why dogs might be a Covid tester ’s best friend7.50pmBSTOfficials have stopped a Covid-19 testing study in theUSafter multiple reports that state and federal public health workers were threatened and face racial slurs.The U.S. Centers for Disease Control and Prevention pulled f...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak World news UK news US news Australia news Science Infectious diseases Source Type: news
Conclusion: The prevalence of bacterial isolates among presumptive patients suspected to BSIs in Ethiopia remains high. Furthermore, we found a remarkable variation in the pathogen distribution across the study setting. PMID: 32963541 [PubMed]
Source: International Journal of Microbiology - Category: Microbiology Tags: Int J Microbiol Source Type: research
Authors: Mishra VN, Kumari N, Pathak A, Chaturvedi RK, Gupta AK, Chaurasia RN Abstract An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan City, China, in December 2019. Since then, the outbreak has grown into a global pandemic, and neither a vaccine nor a treatment for the disease, termed coronavirus disease 2019 (COVID-19), is currently available. The slow translational progress in the field of research suggests that a large number of studies are urgently required. In this context, this review explores the impact of bacteriophages on SARS-CoV-2, especially conce...
Source: International Journal of Microbiology - Category: Microbiology Tags: Int J Microbiol Source Type: research
CONCLUSION: This investigation indicated that cocktail DNA vaccine encoded SAG1 gene of T. gondii and FliC can protect against acute toxoplasmosis. PMID: 31610951 [PubMed - as supplied by publisher]
Source: Biologicals : Journal of the International Association of Biological Standardization - Category: Biotechnology Authors: Tags: Biologicals Source Type: research
Yong Yang1,2†, Xue Bai1†, Chengyao Li1†, Mingwei Tong3, Peihao Zhang2, Wei Cai4, Xiaolei Liu1* and Mingyuan Liu1,5* 1Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Institute of Zoonosis, Jilin University, Changchun, China 2Wu Xi Medical School, Jiangnan University, Wuxi, China 3School of Basic Medical Sciences, Shanxi Medical University, Taiyuan, China 4Affiliated Hospital of Jiangnan University, The Fourth People's Hospital of Wuxi City, Wuxi, China 5Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Di...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Eimeria tenella can cause the disease coccidiosis in chickens. The direct and often detrimental impact of this parasite on chicken health, welfare, and productivity is well recognized; however, less is known about the secondary effects that infection may have on other gut pathogens. Campylobacter jejuni is the leading cause of human bacterial foodborne disease in many countries and has been demonstrated to exert negative effects on poultry welfare and production in some broiler lines. Previous studies have shown that concurrent Eimeria infection can influence the colonization and replication of bacteria, such as Clostridiu...
Source: Infection and Immunity - Category: Infectious Diseases Authors: Tags: Fungal and Parasitic Infections Source Type: research
Publication date: Available online 7 December 2017 Source:Preventive Veterinary Medicine Author(s): Alison K. Howell, Sue C. Tongue, Carol Currie, Judith Evans, Diana J.L. Williams, Tom N. McNeilly Escherichia coli O157 is a zoonotic bacterium that can cause haemorrhagic diarrhoea in humans and is of worldwide public health concern. Cattle are considered to be the main reservoir for human infection. Fasciola hepatica is a globally important parasite of ruminant livestock that is known to modulate its host’s immune response and affect susceptibility to bacterial pathogens such as Salmonella Dublin. Shedding of E. col...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
Author Affiliations open 1Public Health Institute, Oakland, California, USA 2Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA 3Instituto de Microbiologia, Colegio de Ciencias Biologicas y Ambientales, Universidad San Francisco de Quito, Quito, Ecuador 4Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, Michigan, USA 5Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA 6Department of Veterinary and Biomedical Sciences, University of Minnesota, St. Paul, Minnesota, USA PDF Version (176 KB) Abstract ...
Source: EHP Research - Category: Environmental Health Authors: Tags: Brief Communication Source Type: research
This study attempted to reisolate this species of Brucella from rodents living in the boundary area adjacent to WNP and to establish which endo‐ and ecto‐parasites and bacterial agents were being carried by non‐indigenous rodents at this interface. Seventy non‐indigenous rodents were trapped [Mus musculus (52), Rattus rattus (17) and Rattus norvegicus (1)], euthanized and sampled on four properties adjacent to the WNP in July 2012. Organ pools were screened by culture for Salmonella, Leptospira and Brucella species, real‐time PCR for Coxiella burnetii and conventional PCR for Leptospira. Collected ecto‐ and end...
Source: Transboundary and Emerging Diseases - Category: Veterinary Research Authors: Tags: Original Article Source Type: research
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