How To Play Tricks On Artificial Intelligence?

While in the last years, sci-fi stories, experts and even some opinion-leader public figures frequently spelled the end of mankind through artificial intelligence, lately, it turned out just how easy it is to play tricks on smart algorithms and fool them into making errors. We looked around how researchers can hack A.I. and what that means for medicine and healthcare, mainly from a security perspective. Does A.I. have an Achilles heel? As the saying goes, a chain is as strong as its weakest link – and the ancient Greeks knew it. No matter that Achilles had extraordinary strength, courage, and loyalty, that he fought as the bravest in the Trojan war, as a tiny spot on his body was targeted, he was down. Recent examples show that something similar might happen in the back yard of artificial intelligence – if we are not vigilant enough and don’t do the necessary steps to counter it. While in the latest years, we could hear a lot about the power and capabilities of A.I. – even to bring humanity to its knees, recent news talk about the fact that researchers have found the Achilles heel of smart algorithms. Remember when Stephen Hawking said that the development of full artificial intelligence could spell the end of the human race? Or when Elon Musk told Bloomberg’s Ashlee Vance, the author of the biography Elon Musk, that he was afraid that his friend Larry Page, a co-founder of Google and now the C.E.O. of its parent company, Alphabet, could...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Artificial Intelligence Future of Medicine Security & Privacy adversarial adversarial example AI autonomous data security digital digital health hack Healthcare self-driving technology Source Type: blogs

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This study profiled differentially expressed long noncoding RNAs (lncRNAs) in lung squamous cell carcinoma (LSCC) to predict LSCC overall survival (OS) using The Cancer Genome Atlas data. Materials &methods: The RNA-seq and clinical dataset of 475 LSCC patients was retrieved from The Cancer Genome Atlas database and statistically analyzed. Results: There were 67 upregulated and 32 downregulated lncRNAs in LSCCs and 12 lncRNAs associated with OS. The seven-lncRNA signature was associated with poor OS and RP11-150O12.6 and CTA-384D8.35 were associated with better OS (p
Source: Future Medicine: Biomarkers in Medicine - Category: Internal Medicine Tags: Biomark Med Source Type: research
Authors: LeBlanc AG, Jun Gao Y, McRae L, Pelletier C Abstract In 1999, the Government of Canada, along with the provinces and territories, established the National Diabetes Surveillance System (NDSS) to track rates of diabetes in Canada. The NDSS used a novel method to systematically collect and report national diabetes data using linked administrative health databases. The NDSS has since evolved to become the Canadian Chronic Disease Surveillance System (CCDSS) and provides information on over 20 chronic conditions. This At-a-glance report provides the most up-to-date CCDSS information on diabetes rates in Canada....
Source: Health Promotion and Chronic Disease Prevention in Canada - Category: International Medicine & Public Health Tags: Health Promot Chronic Dis Prev Can Source Type: research
We report an optic atrophy spectrum disorder, including retinal macular dystrophy and kidney insufficiency leading to transplantation, associated with mitochondrial DNA (mtDNA) depletion without accumulation of multiple deletions. By whole-exome sequencing, we identified mutations affecting the mitochondrial single-strand binding protein (SSBP1) in 4 families with dominant and 1 with recessive inheritance. We show that SSBP1 mutations in patient-derived fibroblasts variably affect the amount of SSBP1 protein and alter multimer formation, but not the binding to ssDNA. SSBP1 mutations impaired mtDNA, nucleoids, and 7S-DNA am...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Mitochondrial dysfunction or loss is evident in neurodegenerative diseases. Furthermore, mitochondrial DNA (mtDNA) mutations associated with NADH dehydrogenase subunits and nuclear gene mutations that affect mitochondrial function result in optic neuropathies. In this issue of the JCI, Del Dotto et al. and Piro-Mégy et al. identify heterozygous mutations in nuclear-encoded mitochondrial single-strand binding protein 1 (SSBP1) in patients with apparently dominant optic neuropathy with or without extraocular phenotypes. Both research groups reported similar mitochondrial findings in response to SSBP1 mutations. Howeve...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Authors: Nikolajczyk BS, Dawson DR Abstract New strategies are critically needed to counter uncontrolled periodontal infection and inflammation in obesity-associated type 2 diabetes (T2D). However, mechanisms that explain the relationship between periodontitis (PD) and T2D remain poorly understood. Several lines of evidence indicate that destructive immune responses potentiate periodontitis (PD) in T2D. B cells are abundant in periodontal lesions, and our data show that B cells are required for PD in obese/insulin resistant but not lean/normoglycemic mice. In mice and in people, T2D-primed B cells supported Th17 cy...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Belibasakis GN, Hajishengallis G Abstract The 1st International Conference on Oral Mucosal Immunity and the Microbiome (OMIM) took place at the Avra Imperial Hotel, Chania, Crete, Greece, between 26th and 30th September 2018, under the auspices of the Aegean Conferences. This was the first Aegean Conference of its kind in thematic oral research, and a unique blend of immunological and microbiological perspectives, which attracted leading scientists from around the world to discuss the latest advances in the field. The Conference was divided into eight sessions that spanned across 4 days and included the fo...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Contributor : Maria B MonteiroSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensUsing a discovery/validation approach we investigated associations between a panel of genes selected from a transcriptomic study and the renal function decline across time in a cohort of type 1 diabetes patients.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Source: Surgical Clinics of North America - Category: Surgery Authors: Source Type: research
From the first description of an entity akin to our present understanding of Melanoma by Hippocrates of Cos in the fifth century bce, to the coinage of the term (melas “dark,” oma “tumor”) by Carswell in the nineteenth century, not much changed in the understanding or the management of this disease. The next century saw the application of increasingly radical surgery in an attempt to extirpate the disease without appreciable success in the outcomes for adv anced disease. From essentially useless chemotherapy in 1950 to 1980 with dacarbazine, it was not until the 1990s that first glimmer of hope was ...
Source: Surgical Clinics of North America - Category: Surgery Authors: Tags: Preface Source Type: research
We report successful anaesthetic management of an accidental traumatic rupture of the left main bronchus during surgical dissection in an elderly lady of Carcinoma Oesophagus who underwent a Video Assisted Thoracoscopic surgery (VATS), and was managed by one lung ventilation of the contralateral (right) side manipulating the same DLT and lung protective ventilation.
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
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