Therapeutic Applications of Ethanol: A Review.

CONCLUSION: With the development of interventional radio technologies, and thus extremely precise access to anatomical structures, alcohol has been given new indications - particularly as an embolization, sclerosing or ablation agent. Moreover, constant progress in our knowledge of ethanol's pharmacodynamics might highlight other therapeutic indications for this compound in the future. Ethanol's low cost and wide availability make it a valuable therapeutic agent, compared with other reference treatments. Furthermore, ethanol has a long track record of safety and effectiveness in the indications mentioned above. PMID: 31604058 [PubMed - in process]
Source: Journal of Pharmacy and Pharmaceutical Sciences - Category: Drugs & Pharmacology Tags: J Pharm Pharm Sci Source Type: research

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Much has been made lately of millennials drinking less—and as America’s younger generations shift toward sobriety, recent research suggests the opposite is happening among its older ones. A new study published in the Journal of the American Geriatrics Society found that, from 2015-2017, more than 10% of adults 65 and older said they had binge drank—defined as consuming five or more drinks in one sitting for men, or four or more for women— in the past month, up from about 7% in 2006. That’s in keeping with other studies that have charted increases in excessive drinking among elderly adults, inc...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized embargoed study public health Source Type: news
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
When it comes to your beverage of choice, alcoholic beverages are unique. For millions, they are a regular part of the dining experience. They’re often an important component of social events, celebrations, and milestones; we toast people, events, and memories with alcohol. They play a key role in many religious traditions. And, of course, the alcoholic beverage industry is a major economic force, responsible for more than $220 billion in sales annually in the US. And all of this is true despite the well-known and well-publicized risks of drinking too much alcohol. The negative effects of alcohol It should be a surpr...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Alcohol Health Source Type: blogs
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 247 (with a little art contribution from Dr Michelle Johnston) Readers can subscribe to FFFF RSS or subscribe to the FFFF weekly EMAIL Question 1 What is the poison that Socrates is about to voluntarily consume? http://www.metmuseum.org/art/collection/se...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Frivolous Friday Five Aorta brown sequard epilepsy hemlock Jacques Louis David Joseph Lawrence joseph lister Listerine Marat Socrates stabbing Source Type: blogs
This study identifies the missing link between Lewy bodies and the type of damage that's been observed in neurons affected by Parkinson's. Parkinson's is a disorder of the mitochondria, and we discovered how Lewy bodies are releasing a partial break-down product that has a high tropism for the mitochondria and destroys their ability to produce energy." Lewy bodies were described a century ago, but it was not until 1997 that scientists discovered they were made of clumps of a misfolded protein called α-synuclein. When it's not misfolded, α-synuclein is believed to carry out functions related to the ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
The objective is to wind up with the right amount of FOXO4-DRI dissolved in phosphate buffered saline in a sealed vial, ready to be used with the injection system, and with as little contamination as possible from the environment. Depending on the size of the vial, it might contain doses for multiple injections - in fact it is much easier to set things up this way. FOXO4-DRI dissolves very readily in saline, so placing a single human dose into 0.5ml or 1ml is quite feasible. A 3ml vial can hold three doses for the treatment without issue. One approach is to measure out FOXO4-DRI by weight using a suitable microscale...
Source: Fight Aging! - Category: Research Authors: Tags: Self-Experimentation Source Type: blogs
Hot on the heels of headlines linking alcohol consumption with longer life comes new research that casts a much more sobering light on drinking. According to an analysis of more than 1 million people—the largest study of its kind to date—scientists say that heavy alcohol use is the biggest modifiable risk factor for dementia, especially early-onset forms of the disease. The findings, which are published in The Lancet Public Health, came as a shock to the researchers involved. “We hypothesized that alcohol would play some role, but I don’t think anyone expected the size of the effect to be so large,&...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime onetime Research Source Type: news
Conclusions: Our study suggested that incident CHD was positively associated with plasma levels of titanium and arsenic, and inversely associated with selenium. Additional research is needed to confirm these findings in other populations. https://doi.org/10.1289/EHP1521 Received: 22 December 2016 Revised: 17 September 2017 Accepted: 19 September 2017 Published: 19 October 2017 Address correspondence to T. Wu, or A. Pan, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, 13 Hongkong Rd., Wuhan 430030, Hubei, China. Telephone: +86-27-83692347. Email: wut@mails.tjmu.edu.cn or p...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
Naturopathy and naturopaths are a fairly frequent topic on this blog —and for very good reason. If there is an example of a pseudomedical " discipline " that has been gaining undeserved " respectability, " it's naturopathy. It's licensed in all too many states, and physicians who have fallen under the spell of so-called " integrative medicine, " a specialty that rebrands science-based lifestyle medical interventions as somehow " alternative " or " integrative " and uses them as a vessel to " integrate " quackery into medicine, seem to have a special affinity...
Source: Respectful Insolence - Category: Surgery Authors: Source Type: blogs
We examined the association between environmental exposures to lead, mercury, and cadmium and the risk of hearing loss in adults and adolescents while controlling for potential confounding factors, including noise exposures and clinical factors. Methods: We analyzed cross-sectional data from 5,187 adults and 853 adolescents in the Korean National Health and Nutrition Examination Survey 2010–2012. Pure-tone average (PTA) of hearing thresholds at high frequency (3, 4, and 6 kHz) were computed, and hearing loss was defined as a PTA>25 dB in adults and PTA>15 dB in adolescents. Results: In adults, the...
Source: EHP Research - Category: Environmental Health Authors: Tags: Research Source Type: research
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