Mandatory childhood vaccination could cause “irreparable damage,” says expert panel
Publication date: Available online 14 November 2019Source: The Lancet Global HealthAuthor(s): Karoun H Bagamian, John D Anderson, Farzana Muhib, Oliver Cumming, Lindsey A Laytner, Thomas F Wierzba, Richard RheingansSummaryBackgroundDiarrhoea, a global cause of child mortality and morbidity, is linked to adverse consequences including childhood stunting and death from other diseases. Few studies explore how diarrhoeal mortality varies subnationally, especially by cause, which is important for targeting investments. Even fewer examine indirect effects of diarrhoeal morbidity on child mortality. We estimated the subnational d...
Abstract Analysis of the Amino-peptidase N (APN) protein from Anopheles culicifacies as a vector based Transmission Blocking Vaccines (TBV) target has been considered for malaria vaccine development. Short peptides as potential epitopes for B cells and cytotoxic T cells and/or helper T cells were identified using prediction models provided by NetCTL and IEDB servers. Antigenicity determination, allergenicity, immunogenicity, epitope conservancy analysis, atomic interaction with HLA allele specific structure models and population coverage were investigated in this study. The analysis of the target protein helped to...
Condition: Ovarian Cancer Intervention: Drug: W_ova1 Vaccine Sponsors: University Medical Center Groningen; Biontech RNA Pharmaceuticals GmbH Not yet recruiting
Condition: Rabies Interventions: Biological: ChAdOx2 RabG; Biological: Inactivated Rabies Vaccine Sponsor: University of Oxford Not yet recruiting
Condition: Hepatitis B Vaccination Interventions: Biological: Subcutaneous fat injection of Recombivax-HB; Biological: Intramuscular injection of Recombivax-HB Sponsor: University of Maryland, Baltimore Completed
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