Caseous Calcification of the Mitral Annulus: A Role for Surgery

Publication date: Available online 10 October 2019Source: The Annals of Thoracic SurgeryAuthor(s): Vincent Chauvette, Émilie Laflamme, Valérie Lafrenière-Bessi, Mohammed Marzouk, Olivier Bertrand, Kim O’Connor, Mario Sénéchal, Christian Steinberg, Michel Gingras, Pierre Voisine, Frederic JacquesAbstractAn 80 year-old-man followed for aortic stenosis was found to have an intracardiac mass. Multiple imaging modalities were inconclusive in characterizing the mass but raised concerns about the potential malignancy of the mass. Fear of operating on an elderly patient with a potential for cardiac neoplasia led to a percutaneous transseptal biopsy that failed to provide a clear diagnosis. Cardiac valvular surgery was performed in addition to excisional biopsy of the mass that turned out to be caseous necrosis of mitral annular calcifications.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research

Related Links:

Publication date: Available online 21 February 2020Source: Canadian Journal of CardiologyAuthor(s): Alexander Emmott, Vanessa Hertig, Alexandre Bergeron, Louis Villeneuve, Laurence Lefebvre, Richard L. Leask, Angelino Calderone, Ismail El-HamamsyAbstractBackgroundClinical studies have revealed a greater risk of pulmonary autograft dilatation after the Ross procedure in patients with preoperative aortic insufficiency (AI). The present study examined whether the morphological, biomechanical and cellular properties of the pulmonary artery (PA) from patients with AI were phenotypically different compared to patients diagnosed ...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
To assess the phenotypic variations found amongst hearts diagnosed at autopsy with hypoplastic left heart syndrome, with attention to implications related to this syndrome as an acquired disease of fetal life, rather than being the consequence of abnormal embryogenesis. We assessed 119 specimens, from two archives, diagnosed initially as representing hypoplastic left heart syndrome. Among the 119 specimens, the majority of which had been entered into the archives prior to the availability of surgical treatment for the syndrome, 36 (30%) had the combination of mitral and aortic atresia, 26 (22%) had mitral and aortic stenos...
Source: Seminars in Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: CONGENITAL – Original Submission Source Type: research
AbstractSevere aortic stenosis (AS) causes left ventricular (LV) afterload and subendocardial ischemia. Despite this, most infants with AS have normal LV ejection fraction (EF). Strain analysis using two-dimensional speckle tracking echocardiography (2DSTE) may identify more sensitive markers of systolic dysfunction. We sought to show changes in LV strain after balloon aortic valvuloplasty (BAV) in infants with AS. Twenty-seven infants  ≤ 1 year of age with AS who underwent BAV from 2007 to 2017 were included. Echocardiograms before/after BAV were retrospectively analyzed with 2DSTE. Median age was 29...
Source: Pediatric Cardiology - Category: Cardiology Source Type: research
My understanding of the legality and propriety of hospital"advertising" in social media was rather vague but an article on this topic cleared away the cobwebs (see:Hospital Advertising). Below is an excerpt from it. It turns out to be legal but later in the post I will discuss why I think it's beneficial for healthcare consumers.While advertising by doctors and hospitals has been legal for 30 years, until recently, professional taboos discouraged the practice. Increasing economic pressures and changing cultural norms have led, however, to the demise of these informal proscriptions, and advertisements pro...
Source: Lab Soft News - Category: Laboratory Medicine Authors: Tags: Healthcare Business Healthcare Innovations Medical Consumerism Quality of Care Social Media Source Type: blogs
Authors: Saeed S, Dweck MR, Chambers J Abstract Introduction: In aortic stenosis (AS), there are clear sex-differences in clinical presentation, left ventricular (LV) response to pressure overload, and pathophysiology of valvular calcification. These differences may affect outcome following valve intervention.Area covered: This review aims to discuss sex-differences in clinical presentation, pathophysiology of aortic valve calcification, LV remodeling in view of historic and recent echocardiographic and cardiac magnetic resonance imaging studies, and outcome after valve intervention. In addition, it will also provi...
Source: Expert Review of Cardiovascular Therapy - Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research
AbstractBackgroundThe benefit of TAVI in cancer patients is currently unclear.ObjectivesThe purpose of this study is to investigate prognostic impact of cancer status (active cancer or previous cancer) in severe aortic stenosis (AS) patients undergoing transcatheter aortic valve implantation (TAVI).MethodsConsecutive TAVI patients in the Heart Center Bonn were enrolled and we stratified the patients into three groups: current cancer (active cancer), non-current cancer (previous cancer), or no cancer. The primary outcome was all-cause death within a 5-year follow-up. We evaluated mean aortic pressure gradient (mPG) values f...
Source: Clinical Research in Cardiology - Category: Cardiology Source Type: research
The objective of this study was to assess imaging predictors of mitral regurgitation (MR) improvement and to evaluate the impact of MR regression on long-term outcome in patients undergoing transcatheter aortic valve replacement (TAVR).BackgroundConcomitant MR is a frequent finding in patients with severe aortic stenosis but usually left untreated at the time of TAVR.MethodsMitral regurgitation was graded by transthoracic echocardiography before and after TAVR in 677 consecutive patients with severe aortic stenosis. 2-year mortality was related to the degree of baseline and discharge MR. Morphological echo analysis was per...
Source: Clinical Research in Cardiology - Category: Cardiology Source Type: research
Patients with aortic stenosis are nearly twice as likely to have a diagnosis of gout compared with individuals without aortic valve disease.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Clinical Research Study Source Type: research
In conclusion, our study demonstrated that miR-424-3p and miR-3688-3p directly targeted SMAD7 and YAP1 in HASMCs, pivotal genes of the TGF-β and Hippo-signaling pathways. Circulating miR-424-3p was also found to be significantly de creased in BAV patients when compared to TAV patients, especially in patients with aortic stenosis. Further large studies of well-characterized BAV patient cohorts are needed to define the clinical significance of the miR-424-3p.
Source: Heart and Vessels - Category: Cardiology Source Type: research
ri S, Manohar K, Marwah A, Mishra S, Mohanty SR, Murthy KS, Suresh PV, Radhakrishnan S, Rajashekar P, Ramakrishnan S, Rao N, Rao SG, Reddy CH, Sharma R, Shivaprakasha K, Subramanyan R, Kumar RS, Talwar S, Tomar M, Verma S, Raju V, Working group on Management of Congenital Heart Disease in India Abstract JUSTIFICATION: A number of guidelines are available for management of congenital heart diseases from infancy to adult life. However, these guidelines are for patients living in high income countries. Separate guidelines, applicable to Indian children, are required when recommending an intervention for congenital he...
Source: Indian Pediatrics - Category: Pediatrics Authors: Tags: Indian Pediatr Source Type: research
More News: Aortic Stenosis | Cancer & Oncology | Cardiovascular & Thoracic Surgery