Association of Surgical Treatment with Survival in Patients with Prosthetic Valve Endocarditis

This study investigated the association of surgical treatment with survival among patients with PVE.MethodsA retrospective cohort study was done of patients with PVE hospitalized over 8 years in a large referral center. Association of surgery with survival was evaluated using multivariable Cox proportional hazards regression, adjusting for propensity to be accepted for surgery, and analyzing surgery as a time-dependent covariate. Survival was also compared separately in a 1:1 propensity score-matched cohort of patients accepted for surgery and controls consigned to non-surgical treatment.ResultsOf 523 patients (mean [SD] age 61 [14] years, 370 [71%] males, 393 [75%] initially accepted for surgery), 404 ultimately underwent surgery and 119 received non-surgical treatment alone. Surgical treatment was associated with significantly lower hazard of death in the entire cohort (HR 0.32, 95% CI 0.22 to 0.48, P
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research

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This article reports an 82-year-old male with a mechanical aortic valve replacement who was admitted for fever and fatigue. He was diagnosed with a tricuspid valve endocarditis caused by an extended spectrum beta lactamase producing Escherichia coli following positive blood cultures and echocardiography. He received six weeks of imipenem / cilastatin and subsequently improved and was discharged with ambulatory follow ups with his infectious disease specialist.
Source: IDCases - Category: Infectious Diseases Source Type: research
We report a case of successful treatment of relapsed prosthetic valve Enterococcus faecalis endocarditis with oral amoxicillin/clavulanate. Enterococcal endocarditis is associated with a high relapse rate, even with the recommended treatment duration by the guidelines. Oral therapy is increasingly considered as part of the management of such serious infections.Graphical abstract
Source: IDCases - Category: Infectious Diseases Source Type: research
Publication date: November 2019Source: Revista Portuguesa de Cardiologia (English Edition), Volume 38, Issue 11Author(s): Marta Braga, Helena Nascimento, Carla Sousa, Paula Dias, Maria Júlia Maciel, Filipe Macedo
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
Publication date: Available online 21 February 2020Source: American Heart JournalAuthor(s):
Source: American Heart Journal - Category: Cardiology Source Type: research
ConclusionsIn experienced centers, Ross procedure is a reliable alternative to prosthetic or homograft valve replacement in young adults suffering from active aortic valve endocarditis, with a low operative risk and good long-term results.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
CONCLUSIONS: In experienced centers, Ross procedure is a reliable alternative to prosthetic or homograft valve replacement in young adults suffering from active aortic valve endocarditis, with a low operative risk and good long-term results. PMID: 32084372 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research
ConclusionsRobotically assisted mitral valve repair was feasible, safe, and therapeutically effective in the first 100 cases, with a minimal learning curve. The robotically assisted approach provides a high-quality surgical view and tremorless suture/cut handling, which will contribute to further development of minimally invasive mitral valve surgery.
Source: General Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Age is a risk factor for infective endocarditis, and almost half of diagnosed patients are age  ≥ 60 years. Large national studies have not evaluated inpatient mortality and surgical valvular interventions betw...
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Tags: Research article Source Type: research
Publication date: Available online 13 February 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Pengtao Bao, Zengzhen Zhang, Weiguo Zhao, Ying Jiang, Di Wang
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
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