Viruses, Vol. 11, Pages 936: Cross-Protection of Inactivated Rabies Vaccines for Veterinary Use against Bat Lyssaviruses Occurring in Europe

In this study, we demonstrated that the three investigated bat isolates were pathogenic, even at low dose, when inoculated by the central route but were not/less pathogenic when administrated peripherally. The Rabisin vaccine was capable of significantly cross-protecting mice inoculated intramuscularly with EBLV-1b and EBLV-2 and intracerebrally with BBLV. The level of rabies neutralizing antibodies induced by the Rabisin was quite high against the bat lyssaviruses, but with no significant differences between immunization with 1 and 5 IU/dose. The study emphasizes that the quality of rabies-inactivated vaccines for veterinary use is of utmost importance to optimize the cross-protection of pets against phylogroup I bat lyssaviruses occurring in Europe.
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research

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Publication date: Available online 12 November 2019Source: Preventive Veterinary MedicineAuthor(s): Felipe Rocha, Ricardo Augusto DiasAbstractThe importance of the common vampire bat Desmodus rotundus for the transmission of the rabies virus does not lie solely in its ability to transmit this disease to other mammals, but also in its capacity to adapt to environmental and climatic changes, granting them a wide geographical distribution. Control of this disease is currently based on culling of the vampire bat and vaccination of the livestock. A transmission model incorporating geographic and behavioral determinants of the v...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
CONCORD, N.H. (AP) — New Hampshire health officials are requesting the public’s help in finding a man from Massachusetts to assess his risk for rabies after he came into contact with baby raccoons. Health officials say the man was in Conway at about 5 p.m. on Sept. 20 and stopped to help someone remove two baby raccoons on Route 16 between North Bald Hill Thorn Hill roads. The raccoons were brought to a wildlife rehabilitation center, where one died and was identified to have rabies. The other didn’t have rabies. Health officials said Friday the man, who drove a dark pickup truck with oversized tires and ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Offbeat Syndicated CBSN Boston New Hampshire News Rabies raccoons Source Type: news
g Sun Gao Yang Zhao Xia Rift Valley fever virus (RVFV), which causes Rift Valley fever (RVF), is a mosquito-borne zoonotic pathogen that causes serious morbidity and mortality in livestock and humans. RVF is a World Health Organization (WHO) priority disease and, together with rabies, is a major health burden in Africa. Here, we present the development and characterization of an inactivated recombinant RVFV and rabies virus (RABV) vaccine candidate (rSRV9-eGn). Immunization with rSRV9-eGn stimulated the production of RVFV-specific IgG antibodies and induced humoral and cellular immunity in mice but did n...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
In this study, a geographical area within the central region of Portugal (municipalities of Proença-a-Nova, Mação and Vila de Rei) was investigated. An epidemiological survey involved the analysis by an indirect enzyme-linked immunosorbent assay of serum samples collected during the anti-rabies vaccination campaign from 282 dogs. Geospatial analysis showed the distribution of geospatial prevalence of leishmaniosis and has delimited two areas (clusters) with a statistically significant higher risk of seropositivity in dogs (p =  0.003 and p = 0.027, for clusters 1 and 2, respectively). The...
Source: Veterinary Parasitology - Category: Veterinary Research Source Type: research
The objective of this paper is to estimate how dog rabies vaccinations affect human rabies deaths, mediated through dog rabies cases, dog bite reporting, and post-exposure human rabies vaccination. To approach this objective, we apply multivariate regression analysis over five rabies-related outcomes: (a) dog vaccinations, (b) dog rabies cases, (c) reported human exposures, (d) human post-exposure prophylaxis (PEP) use, and (e) human rabie s cases. Analysis uses aggregate annual data over 1995–2005 for seven Latin American countries that experienced dramatic declines in canine and human rabies. Among other results, w...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Conclusion: The incidence of animal exposure was 1.26%. Rabies PEP in the cases was not satisfactory.
Source: Indian Journal of Public Health - Category: International Medicine & Public Health Authors: Source Type: research
Conclusions: Health-seeking behavior and compliance to complete course of anti-rabies vaccination is unsatisfactory, which has to be improved to prevent rabies.
Source: Indian Journal of Public Health - Category: International Medicine & Public Health Authors: Source Type: research
Conclusion: The facilities available for PEP at the anti-rabies clinics were inadequate and have to be improved across the country.
Source: Indian Journal of Public Health - Category: International Medicine & Public Health Authors: Source Type: research
Conclusions: There are many lacunas in the market availability of rabies biologicals in different parts of the country; therefore, a significant expansion/shift in focus must be considered, through rigorous strategic planning process.
Source: Indian Journal of Public Health - Category: International Medicine & Public Health Authors: Source Type: research
;chenne M Abstract To prevent human rabies deaths close communication between the veterinary and human health sector is needed for timely and adequate treatment after a bite exposure. Good practice treatment and efficient One Health communication depends heavily on the knowledge and practices (KP) of both human health and veterinary workers. We have evaluated the level of KP of both these sectors during a one-day joint training program to kick start a large scale rabies burden and vaccine demand study in selected regions of Chad. Participants were evaluated through a questionnaire before and after training to get ...
Source: Acta Tropica - Category: Infectious Diseases Authors: Tags: Acta Trop Source Type: research
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