Being Overweight Wipes 4 Years From Life, New Report Reveals Being Overweight Wipes 4 Years From Life, New Report Reveals

"What we have done is not enough," says influential group as it launches a grim global report showing people are becoming heavier. Policies work, and will generate savings, but implementation is essential.Medscape Medical News
Source: Medscape General Surgery Headlines - Category: Surgery Tags: Diabetes & Endocrinology News Source Type: news

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Conclusion. Patients with higher BMI had lower preoperative PROMIS PF scores and experienced similar improvement in PROMIS PF scores in the postoperative period. This study established that PROMIS PF may be utilized to evaluate the recovery of obese patients following MIS TLIF. Level of Evidence: 3
Source: Spine - Category: Orthopaedics Tags: OUTCOMES Source Type: research
Authors: Lega IC, Lipscombe LL Abstract Obesity and diabetes have both been associated with an increased risk of cancer. In the face of increasing obesity and diabetes rates worldwide, this is a worrying trend for cancer rates. Factors such as hyperinsulinemia, chronic inflammation, anti-hyperglycemic medications and shared risk factors have all been identified as potential mechanisms underlying the relationship. The most common obesity- and diabetes-related cancers are endometrial, colorectal and post menopausal breast cancers. In this review, we summarize the existing evidence that describes the complex relations...
Source: Endocrine Reviews - Category: Endocrinology Tags: Endocr Rev Source Type: research
ConclusionsDiabetic nephropathy was common among Chinese patients with type 2 diabetes in primary care in Hong Kong. Early identification and control of the modifiable risk factors are of upmost importance in preventing the complication.
Source: Journal of Diabetes and Metabolic Disorders - Category: Endocrinology Source Type: research
Around 13million people over the age of 16 were considered obese in 2017 - up from the 6.9million recorded back in 1997, according to the analysis by the charity Diabetes UK.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Contributors : Martin G Scherm ; Carolin Daniel ; Benedikt KirchnerSeries Type : Non-coding RNA profiling by high throughput sequencingOrganism : Homo sapiensIn type 1 diabetes (T1D), the appearance of multiple islet autoantibodies indicates the onset of islet autoimmunity, often many years before clinical symptoms arise. However, the underlying molecular mechanisms in T cells that can promote aberrant activation thereby triggering autoimmune progression remain poorly understood. Here, we show that during early stages of islet autoimmunity a miRNA142-3p/Tet2 signaling axis in murine and human CD4+T cells interferes with th...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by high throughput sequencing Homo sapiens Source Type: research
Contributors : Martin G Scherm ; Carolin Daniel ; Jonathan SchugSeries Type : OtherOrganism : Homo sapiensIn type 1 diabetes (T1D), the appearance of multiple islet autoantibodies indicates the onset of islet autoimmunity, often many years before clinical symptoms arise. However, the underlying molecular mechanisms in T cells that can promote aberrant activation thereby triggering autoimmune progression remain poorly understood. Here, we show that during early stages of islet autoimmunity a miRNA142-3p/Tet2 signaling axis in murine and human CD4+T cells interferes with the efficient induction of regulatory T (Treg) cells a...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Other Homo sapiens Source Type: research
Publication date: Available online 13 November 2019Source: Clinica Chimica ActaAuthor(s): Xin Zeng, Yuan-jie Xie, Ya-ting Liu, Shuang-lian Long, Zhong-cheng MoAbstractPolycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disease characterized by clinical or laboratorial hyperandrogenism, oligo-anovulation and metabolic abnormalities, including insulin resistance, excessive weight or obesity, type II diabetes, dyslipidemia and an increased risk of cardiovascular disease. The most significant clinical manifestation of PCOS is hyperandrogenism. Excess androgen profoundly affects granulosa cell function and...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Obesity and related metabolic disorders, including type 2 diabetes mellitus (T2DM), alarmingly grow up in the modern society thus representing a serious issue for endocrinology and medicine. Obesity is the major risk factor for T2DM [1], however, not all obese individuals ultimately develop T2DM. Nevertheless, mechanisms linking obesity to T2DM are being extensively studied.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
We present a narrative review of HCC in Africa, discussing present and future trends. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Seminars in Liver Disease - Category: Gastroenterology Authors: Tags: Review Article Source Type: research
The metabolic syndrome (MetS) comprises abdominal obesity, preclinical or full diabetes type 2, arterial hypertension, and dyslipidemia and affects a significant proportion of the general population with a remarkably higher prevalence in patients suffering from psychiatric disorders. However, studies exploring the pathogenetic link between MetS and psychiatric diseases are rare. Here, we aim to narrow this gap in knowledge by providing a narrative review on this topic that focuses on two psychiatric diseases, namely on schizophrenia and posttraumatic stress disorder (PTSD) since we assume them to be associated with two dif...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
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