Role of Ischemia Modified Albumin Serum Levels as an Oxidative Stress Marker in Children with Diabetic Ketoacidosis.

Role of Ischemia Modified Albumin Serum Levels as an Oxidative Stress Marker in Children with Diabetic Ketoacidosis. Comb Chem High Throughput Screen. 2019 Oct 08;: Authors: Yazıcı MU, Ayar G, Savas-Erdeve S, Azapağası E, Neşelioğlu S, Erel Ö, Çetinkaya S Abstract AIM AND OBJECTIVE: Ischemia modified albumin (IMA) is a biomarker that has been introduced recently for use in the evaluation of the oxidative stress. The aim of this study was to measure the ischemia modified albumin serum levels in pediatric patients with diabetic ketoacidosis (DKA) during acidosis and after the patient recovered from acidosis and to compare these with the control group. MATERIAL AND METHODS: Pediatric patients with Type I diabetes mellitus (T1DM), who were admitted to the pediatric intensive care unit with the diabetic ketoacidosis were assigned as the study group and healthy children who were admitted to outpatient clinic and decided as healthy after clinic and laboratory evaluation were selected as the control group. IMA and adjusted IMA levels were evaluated in the blood samples from the control group and the study group when the first time admitted to the intensive care unit during the acidosis period (DKA before treatment, DKA-BT), and after recovered from acidosis (DKA after treatment, DKA-AT). RESULTS: A total of 24 pediatric patient with diabetic ketoacidosis and 30 healthy control child matching age and sex were included in the current st...
Source: Combinatorial Chemistry and High Throughput Screening - Category: Chemistry Authors: Tags: Comb Chem High Throughput Screen Source Type: research

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