Overlapping of new leprosy cases in household contact networks in two municipalities in North and Northeast Brazil, 2001-2014.

[Overlapping of new leprosy cases in household contact networks in two municipalities in North and Northeast Brazil, 2001-2014]. Cad Saude Publica. 2019;35(10):e00014419 Authors: Reis ADSD, Souza EA, Ferreira AF, Silva GVD, Macedo SF, Araújo OD, Cruz JR, García GSM, Carneiro MAG, Barbosa JC, Ramos AN Abstract The study aimed to analyze the magnitude and sociodemographic profile of leprosy cases linked to household contact networks with overlapping of the disease in two Brazilian municipalities (counties), one in the North and the other in the Northeast, from 2001 to 2014. This was a cross-sectional, descriptive, analytical study based on primary and secondary data from new leprosy cases in Picos, Piauí State, and Rolim de Moura, Rondônia State. "Overlapping" was defined as new cases with the occurrence of at least one more leprosy case in the individual's household contact network. Each household contact network consisted of the index case (first reported case), co-prevalent cases (contacts that became new cases), and household contacts of the index case. A total of 437 new cases treated by the INTEGRAHANS North-Northeast and Piauí projects were assessed, of which 287 (65.7%) were in Picos and 150 (34.3%) in Rolim de Moura. Of all the cases assessed, 129 (44.9%) in Picos and 98 (65.3%) in Rolim de Moura reported overlapping. There were proportionally more females in Rolim de Moura (n = 95, 63.3%) and males in P...
Source: Cadernos de Saude Publica - Category: International Medicine & Public Health Authors: Tags: Cad Saude Publica Source Type: research

Related Links:

AbstractLeprosy is a chronic infectious disease of the skin and peripheral nerves that presents a strong link with the host genetic background. Different approaches in genetic studies have been applied to leprosy and today leprosy is  among the infectious diseases with the greatest number of genetic risk variants identified. Several leprosy genes have been implicated in host immune response to pathogens and point to specific pathways that are relevant for host defense to infection. In addition, host genetic factors are also inv olved in the heterogeneity of leprosy clinical manifestations and in excessive inflammatory...
Source: Human Genetics - Category: Genetics & Stem Cells Source Type: research
We report a case of resistant bacilli in late reaction and discuss the implications of this finding. PMID: 31707970 [PubMed - as supplied by publisher]
Source: Tropical Doctor - Category: Tropical Medicine Authors: Tags: Trop Doct Source Type: research
In 2013, Lepra Bangladesh (a non-government organization) and the National Leprosy Programme of the Directorate General of Health Services under the Ministry of Health and Family Welfare, Bangladesh implemente...
Source: BMC Health Services Research - Category: General Medicine Authors: Tags: Research article Source Type: research
Authors: Thangaraju P, Venkatesan AS PMID: 31665397 [PubMed - as supplied by publisher]
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
by Diana N. J. Lockwood, Saba Lambert, Aparna Srikantam, Joydeepa Darlong, V. V. Pai, C. Ruth Butlin, Barbara de Barros, Edessa Negera, Stephen L. Walker
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
Authors: Pradana KA, Widjaya MA, Wahjudi M Abstract In Human, Major Histocompatibility Complex known as Human Leukocyte Antigen (HLA). The HLA grouped into three subclasses regions: the class I region, the class II region, and the class III region. There are thousands of polymorphic HLAs, many of them are proven to have correlations with diseases. Indonesia consists of diverse ethnicity people and populations. It carries a unique genetic diversity between one and another geographical positions. This paper aims to extract Indonesians HLA allele data, mapping the data, and correlating them with global diseases. From ...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
ABSTRACT This paper reviews aspects of the life and work of Professor Louis Ranvier 140 years after the publication of Le çons sur l ’ histologie du syst ème nerveux, published in 1878, and shows the importance of the histological description of myelinated fibers of the nodes of Ranvier.RESUMO Os autores apresentam uma revis ão sobre aspectos da vida e obra do Professor Louis Ranvier 140 anos após a publicação de seu livro Leçons sur l ’ histologie du syst ème nerveux publicado em 1878 e mostra a importância da descrição histológ...
Source: Arquivos de Neuro-Psiquiatria - Category: Neurology Source Type: research
DiscussionEven in this previously highly VL endemic area, PKDL is a rare condition. Nevertheless, even a single case can trigger a new VL outbreak. Leprosy is also a rare disease, but current prevalence is over 17 times the elimination threshold proclaimed by WHO. Both diseases require continued surveillance. Active case finding for leprosy can be recommended among household members and close neighbors of leprosy patients but would not be feasible for entire populations. Periodic skin camps may be a feasible and affordable alternative.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
In conclusion, this review reported that IL-37 has a crucial role in reducing infection-associated inflammation and has a good impact on inflammation-induced pathology. However, tight regulation that achieved balance between effector immune responses that required for pathogen elimination and limited tissue damage that resulted from excessive inflammation should be existed in the potential IL-37 therapy to prevent clinical complications of a disease. PMID: 31633447 [PubMed - as supplied by publisher]
Source: International Reviews of Immunology - Category: Allergy & Immunology Tags: Int Rev Immunol Source Type: research
Abstract In Type II lepromatous reaction, there is exacerbation of humoral immunity, classified as Gell &Coombs Type III hypersensitivity reaction. It is more common in lepromatous borderline (LB) and lepromatous lepromatous (LL) patients. Our objective was to study the clinical and laboratorial expressions of lepromatous Type II reactions, establishing concordances between them, and for this the medical records of leprosy patients observed at the Clementino Fraga Filho University Hospital of the Federal University of Rio de Janeiro (HUCFF/UFRJ) were reviewed. There were a total of 358 leprosy cases over a per...
Source: Skinmed - Category: Dermatology Authors: Tags: Skinmed Source Type: research
More News: Brazil Health | International Medicine & Public Health | Leprosy | Study