How Much? Pfizer And Teva Reach $2.1B Deal Over Patent Dispute

This is an example of why at-risk launches are, well, risky. After nearly a decade of squabbling, Teva Pharmaceutical and Sun Pharmaceutical have agreed to settle a heated patent dispute with Pfizer over the Protonix acid-reflux by paying $2.15 billion. More specifically, Teva will shell out $1.6 billion – half this year and half next year - and Sun will pay the rest. At issue was a bet by Teva to begin selling a generic version of Protonx in December 2007 while simultaneously challenging the patent on the medicine that, at the time, was sold by Wyeth, which Pfizer subsequently acquired. The hope was that Teva, which has been a progenitor of at-risk launches, would ultimately prevail in the litigation. But this particular gambit began to sour after a jury decided three years ago that Teva infringed the patent, setting up a new round of sparring over damages to be awarded. Now, the generic drug maker will absorb the first such loss for attempting the tactic. Teva, by the way, faced paying triple damages. Sun also launched a generic in 2008, which explains its role in the deal (here is the lawsuit and the patent). “This is the first case where a generic company is paying damages for an at-risk launch,” writes Sanford Bernstein analyst Ronny Gal in an investor note. “It is an important milestone, setting a ‘book end’ case for the industry. It will serve – and served already, as the outcome was expected – to encourage patent settlem...
Source: Pharmalot - Category: Pharma Commentators Authors: Source Type: blogs

Related Links:

AbstractThis video shows the case of a 64-year-old morbidly obese woman, with a non-adjustable gastric band, who consulted for weight regain and gastroesophageal reflux disease (GERD) symptoms and was converted to Roux-en-Y gastric bypass (RYGB). The operative technique included extensive lysis of adhesions, complete band dissection, partial gastrectomy of the fundus and body due to band erosion and conversion to RYGB.
Source: Obesity Surgery - Category: Surgery Source Type: research
Outcomes of gastroesophageal reflux disease (GERD) using Toupet fundoplication (TF) and Stretta radiofrequency (SRF) have not been compared and this study was conducted to compare therapeutic efficacy of the t...
Source: BMC Gastroenterology - Category: Gastroenterology Authors: Tags: Research article Source Type: research
Endoscopy DOI: 10.1055/a-1171-3174ESGE suggests flexible endoscopic treatment over open surgical treatment as first-line therapy for patients with a symptomatic Zenker’s diverticulum of any size.Weak recommendation, low quality of evidence, level of agreement 100 %.ESGE recommends that emerging treatments for Zenker’s diverticulum, such as Zenker’s peroral endoscopic myotomy (Z-POEM) and tunneling, be considered as experimental; these treatments should be offered in a research setting only.Strong recommendation, low quality of evidence, level of agreement 100 %.ESGE recommends against the widespread c...
Source: Endoscopy - Category: Gastroenterology Authors: Tags: Guideline Source Type: research
The reflux of noxious contents of the stomach may cause oesophageal and extra-oesophageal complications either by direct contact of aspirated gastric refluxate with the upper airway or by a vago-vagal reflex. ...
Source: BMC Gastroenterology - Category: Gastroenterology Authors: Tags: Research article Source Type: research
Conditions:   Gastro Esophageal Reflux;   Barrett Esophagus;   Bariatric Surgery Candidate Intervention:   Drug: Lansoprazole oral tablets 30 mg Sponsor:   University of Roma La Sapienza Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSION: There is mixed evidence with a high degree of bias and heterogeneity between studies for the modalities presented in the paper. Based on this review, an anti-reflux diet is recommended for all patients and there is some low-quality evidence to support alkaline water. For patients with predominant vocal symptoms there is evidence that supports voice therapy. There is insufficient evidence to recommend prokinetics at this time. For patients with predominant globus symptoms, alginate, RKT, and relaxation strategies may be used in conjunction with acid suppressing medications for symptom relief. PMID: 32449369...
Source: The Annals of Otology, Rhinology, and Laryngology - Category: ENT & OMF Authors: Tags: Ann Otol Rhinol Laryngol Source Type: research
Conditions:   Gastro Esophageal Reflux;   Barrett Esophagus;   Bariatric Surgery Candidate Intervention:   Drug: Lansoprazole oral tablets 30 mg Sponsor:   University of Roma La Sapienza Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
No abstract available
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Invited Commentaries Source Type: research
Objective: The aim of the study was to compare the rates of nutrients consumption in children and adolescents with gastroesophageal reflux disease (GERD) compared to the control group without the disease. Methods: Based on symptom evaluation and esophageal pH-impedance recordings patients were allocated on to GERD and control groups. All patients underwent esophagogastroscopy. Levels of nutrients consumption were assessed with the use of food frequency questionnaire in the regard to the presence of the disease, esophagitis, and z score body mass index (BMI). Results: Data of 219 children and adolescents were availa...
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research
Conclusions: Commercial food-based formulas and home prepared blends vary greatly in viscosity, ranging from thin to extremely thick liquids, with the majority achieving viscosity greater than thickened formula. Viscosity is reduced by addition of free water and with freezing and thawing. These data can inform the clinical choice of feeding regimen depending on the goals of nutritional therapy.
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Original Articles: Gastroenterology Source Type: research
More News: Acid Reflux | Gastroesophageal Reflux Disease | GERD | Lawsuits | Legislation | Pantoprazole | Pfizer | Pharma Commentators | Protonix