Altered Cytotoxicity Profile of CD8+ T cells in Ankylosing Spondylitis

ConclusionAS patients have an altered cytotoxic T cell profile. This data suggests that CD8+ T cells with a cytotoxic phenotype are being recruited to the joints, where they possess an activated phenotype. Thus, a central role for CD8+ T cells in AS may have been overlooked and deserves further study.

Source: Arthritis and Rheumatology - October 9, 2019 Category: Rheumatology Authors: Eric Gracey, Yuchen Yao, Zoya Qaiyum, Melissa Lim, Michael Tang, Robert D Inman Tags: BRIEF REPORT Source Type: research