PICCs With Magnetized Tip Linked to Serious Allergic Reactions PICCs With Magnetized Tip Linked to Serious Allergic Reactions

Reactions were much more common in patients with cystic fibrosis and those with previously identified environmental or drug allergies.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Allergy & Clinical Immunology News Source Type: news

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BackgroundChronic rhinosinusitis (CRS) is associated with bronchiectasis; however, this relationship has not been well studied in the United States (US) population. In this work we aimed to determine the prevalence of CRS among patients with bronchiectasis affiliated with a US tertiary medical center and identify which comorbid diseases are associated with the presence of CRS in patients with bronchiectasis.MethodsThis was a retrospective cohort study in which data were obtained from a large database warehouse at a tertiary care center. Patients with bronchiectasis were identified from 2007 to 2017 using diagnosis codes fr...
Source: International Forum of Allergy and Rhinology - Category: Allergy & Immunology Authors: Tags: ORIGINAL ARTICLE Source Type: research
This study assessed omalizumab outcomes in real-world patients with allergic asthma stratified by pretreatment biomarker levels. METHODS: Patients with allergic asthma aged ≥12 years initiated on omalizumab with ≥12 months of data after index were identified in the Allergy Partners electronic medical records (2007-2018). Patients with ≥1 diagnosis of chronic obstructive pulmonary disease in combination with ≥10 pack-years of smoking, cystic fibrosis, Alpha-1 antitrypsin deficiency, bronchiectasis, interstitial lung disease, and sarcoidosis in the 12 months before or after index were excluded. Patients were...
Source: Clinical Therapeutics - Category: Drugs & Pharmacology Authors: Tags: Clin Ther Source Type: research
PMID: 31550169 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - Category: ENT & OMF Authors: Tags: Am J Rhinol Allergy Source Type: research
Polymyxins, namely colistimethate sodium (colistin or polymyxin E) and polymyxin B, are used for multi-drug resistant gram-negative bacterial infections, including Pseudomonas aeruginosa and Acinetobacter baumannii 1. As treatments and therapy have advanced, patients with cystic fibrosis are living longer. However, these patients have high exposure to intravenous antibiotics, most commonly penicillins, cephalosporins, and aminoglycosides. With colonization or infections with resistant gram-negative bacilli, the exposure to antibiotics broadens to include the polymyxins.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Letters Source Type: research
BackgroundThere is a paucity of data evaluating antibiotic use in anterior skull ‐base surgery (ASBS). The goal of this study was to determine antibiotic prescribing patterns and factors that influence antibiotic use in ASBS.MethodsAn online ‐based survey was distributed to the membership of the North American Skull Base Society in 2018. Outcomes included practitioner preference regarding intraoperative and postoperative antibiotic use, practice location and environment, surgeon experience, and patient factors influencing antibiotic u se.ResultsThere were 208 respondents (25.6% response rate) of which 182 (87.5%) perfo...
Source: International Forum of Allergy and Rhinology - Category: Allergy & Immunology Authors: Tags: ORIGINAL ARTICLE Source Type: research
PMID: 31430187 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - Category: ENT & OMF Authors: Tags: Am J Rhinol Allergy Source Type: research
AbstractPurpose of reviewTo explain the underlying pathophysiology of cystic fibrosis and to describe current treatment modalities for disease manifestations, including an introduction to novel therapies known as CFTR modulator drugs, which are now available to over 50% of people with cystic fibrosis.Recent findingsCFTR modulator drugs, aimed at restoring CFTR protein function, have been shown to improve lung function and reduce pulmonary exacerbations, improve BMI and QOL, and are a new added treatment to the traditional therapies for cystic fibrosis.SummaryWith the current modalities of treatment available to patient wit...
Source: Current Treatment Options in Allergy - Category: Allergy & Immunology Source Type: research
The type I receptor for advanced glycation end-products (RAGE) belongs to the immunoglobulin superfamily and is abundantly expressed in the lungs, notably in type 1 alveolar epithelial cells.1 As such, RAGE has been implicated in lung development and in the pathogenesis of chronic lung diseases ranging from cystic fibrosis to asthma.1
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Editorial Source Type: research
CONCLUSION: Metronidazole, tinidazole, and nitazoxanide are the drugs of choice. Resistance to common antigiardial drugs has increased in recent years. As such, the search for new molecular targets for antigiardial drugs is urgently needed. In general, treatment of asymptomatic carriers is not recommended. Purification of water supply is an important preventive measure. PMID: 31210116 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research
Pediatric Allergy, Immunology, and Pulmonology,Volume 32, Issue 2, Page 45-51, June 2019.
Source: Pediatric, Allergy, Immunology, and Pulmonology - Category: Respiratory Medicine Authors: Source Type: research
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