Human virome in nasopharynx and tracheal secretion samples.
CONCLUSIONS: Wide virus diversity was found by different methodologies and high frequency of rhinovirus occurrence was confirmed in population in winter, showing its relevance for public health. PMID: 31596309 [PubMed - in process]
In this study, we included a total of 834 cases consisting of sudden death cases from infantile-pediatric age group and autopsy cases from> 18 year age group with suspected respiratory tract infection in our laboratory between January 2013 and May 2017. Of 834 cases, 468 (56.1%) were male and 366 (43.9%) were female, there were 191 (22.9%) cases between 0-1 months, 593 (71.1%) cases between 1 month-18 years, and 50 (6%) cases in the> 18 years age group. In 728 of 834 (87.3%) cases nasopharyngeal/tracheal swab samples and in 106 (12.7%) of them paraffin-embedded lung tissue samples were studied by the use of "FTD...
Conclusions: Viral pathogens were encountered in one-third of hospitalized adult and pediatric Egyptian patients with SARI, while atypical bacteria had a minor role. Highest rates of viral infections were reported for RSV, PIV, and adenovirus. Viral infections had neither negative impacts on clinical features nor outcomes of patients with SARI in our locality. PMID: 30976418 [PubMed]
ConclusionsViral pathogens were encountered in one-third of hospitalized adult and pediatric Egyptian patients with SARI, while atypical bacteria had a minor role. Highest rates of viral infections were reported for RSV, PIV, and adenovirus. Viral infections had neither negative impacts on clinical features nor outcomes of patients with SARI in our locality.
CONCLUSION: Our results demonstrated the increased sensitivity of molecular detection methods compared with conventional methods for the diagnosis of ARTIs in hospitalized children. This is the first report of HMPV infections in Malaysia. PMID: 30910688 [PubMed - as supplied by publisher]
ConclusionsSpectrum of viral etiologies of ALRTI is highlighted. Etiological diagnosis of ALRTI would enable specific antiviral therapy, restrict antibiotic use and help in knowing burden of disease.
This study gives us better information on the respiratory pathogen profile and coinfection combinations which are important for diagnosis and treatment of ARIs. PMID: 30510579 [PubMed]
Viral respiratory tract infections have been associated with acute exacerbations of COPD (AECOPD). We evaluated longitudinally the incidence of viral infections and their association to AECOPD.We followed 450 patients with stable, moderate to very severe COPD, for 27 months. Detection of 18 viruses (adenovirus, influenza A-B, H1-H3, parainfluenza 1-4, RSV A-B, rhinovirus (RV)/enterovirus, coronavirus NL63, -OC43, -229E, -HKU1, bocavirus and metapneumovirus) was performed in naso- and oropharyngeal swabs collected at URTI onset (n=391), 10 days thereafter (n=356), at AECOPD (n=177) and stable periods (n=1909) using multiple...
Conclusion: There is a high prevalence of respiratory virus infections in immunocompromised patients undergoing diagnostic bronchoscopy for respiratory symptoms. This finding may influence patient management.
Conclusion: The results suggest that children with acute febrile illness in Zanzibar rapidly clear respiratory tract infections but frequently acquire new infections within 14 days.
AbstractDespite increased understanding of how viral infection is involved in asthma exacerbations, it is less clear which viruses are involved and to what extent they contribute to asthma exacerbations. Here, we sought to determine the prevalence of different respiratory viruses during asthma exacerbations. Systematic computerized searches of the literature up to June 2017 without language limitation were performed. The primary focus was on the prevalence of respiratory viruses, including AdV (adenovirus), BoV (bocavirus), CoV (coronavirus), CMV (cytomegalovirus), EnV (enterovirus), HSV (herpes simplex virus), IfV (influe...