Preliminary Findings of a Dedicated Ocular Myasthenia Gravis Rating Scale: The OMGRate

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Source: Neuro-Ophthalmology - Category: Opthalmology Authors: Source Type: research

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Conclusions about the regulation of the MuSK kinase that were derived from molecular structures will be highlighted. In addition, the role of MuSK during development and disease will be discussed.
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
In conclusion, the presence of neither anti-titin nor anti-MuSK antibodies points to unfavorable outcome. Prednisone and azathioprine combination has beneficial effects in non-thymomatous generalized LOMG.
Source: Acta Neurologica Belgica - Category: Neurology Source Type: research
Treatment of Lambert-Eaton myasthenic syndrome (LEMS) in adults.
Source: FDA Center for Drug Evaluation and Research - What's New - Category: Drugs & Pharmacology Authors: Source Type: news
Condition:   Ocular Myasthenia Gravis Intervention:   Drug: Symptomatic Treatment, Steroids, Immunosuppressive Agents( azathioprine, tacrolimus, Mycophenolate Mofetil) Sponsor:   Tang-Du Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Thymoma is a rare tumor that originates from thymic epithelial cells and is usually associated with myasthenia gravis. Radiofrequency ablation (RFA) is a minimally invasive and curative treatment for other tum...
Source: Cancer Imaging - Category: Radiology Authors: Tags: Research article Source Type: research
AbstractMany neurological diseases may cause acute respiratory failure (ARF) due to involvement of bulbar respiratory center, spinal cord, motoneurons, peripheral nerves, neuromuscular junction, or skeletal muscles. In this context, respiratory emergencies are often a challenge at home, in a neurology ward, or even in an intensive care unit, influencing morbidity and mortality. More commonly, patients develop primarily ventilatory impairment causing hypercapnia. Moreover, inadequate bulbar and expiratory muscle function may cause retained secretions, frequently complicated by pneumonia, atelectasis, and, ultimately, hypoxe...
Source: Neurological Sciences - Category: Neurology Source Type: research
Authors: Ruiz Sánchez JG, Marcelo Calvo C, Rico Briñas M PMID: 31780213 [PubMed - as supplied by publisher]
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
A 33-year-old man presented to the emergency department (ED) with a 6-week history of intermittent migratory upper and lower extremity weakness. The ED visit was prompted by a fall caused by severe lower extremity weakness. Further evaluation revealed that the patient had been having significant difficulty with activities of daily living, including bathing, dressing, and eating during the past month, and his symptoms were exacerbated after warm showers. The physical examination revealed right-sided ptosis (Figure  1) with intact extraocular movements.
Source: The Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Visual Diagnosis in Emergency Medicine Source Type: research
ConclusionsRegular intravenous immunoglobulins combined with low-dose immunosuppression in addition to thymectomy appear to be safe when myasthenia gravis occurs in association with Good syndrome.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Conclusions: Treatment for DHS starts with accurate diagnosis of the underlying etiology and is often associated with neuromuscular disease. A treatment algorithm for appropriate management of these patients was proposed. A trial of medical management and/or immunomodulators is warranted. Failing nonoperative management, surgery is predictive of a positive outcome. Level of Evidence: Level V.
Source: Journal of Spinal Disorders and Techniques - Category: Surgery Tags: Systematic Review Source Type: research
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