Sarah Murnaghan, 10, gets adult lung transplant she fought for
A week after judge ruled that Sarah Murnaghan could be considered for adult lungs, her lungs arrived
Specialized T cells in induced bronchus-associated lymphoid tissue regulate alloimmune responses in the lung allograft.
We read with great interest the review by Yanagawa et al, entitled Surgery for tumors of the heart,1 where the authors thoroughly review cardiac tumors classification, diagnosis sequence as well as the suggested method of treatment for the different kinds of tumors. The authors address sarcoma's as one of the rare malignant tumors and suggest a two-step surgical approach to sarcoma that involve the heart and lung.
Zerina Nelson, four, of Mesa, Arizona, was diagnosed with Hermansky-Pudlak syndrome, a genetic condition characterized by albinism and vision considered legally blind
Conditions: Lung Transplant Rejection; Antibody-mediated Rejection Interventions: Drug: Belatacept; Drug: Carfilzomib Sponsors: Duke University; Bristol-Myers Squibb Not yet recruiting
We present a case of endobronchial fusariosis following bilateral sequential lung transplantation for idiopathic pulmonary arterial hypertension in a 13 years old boy who was treated successfully with posaconazole and nebulized amphotericin B. We discuss the role of nebulized amphotericin B in treating invasive pulmonary fungal disease in children. To our knowledge, this is the first pediatric case of endobronchial fusariosis reported in the literature.
Chronic lung allograft dysfunction or CLAD, encompasses a variety of phenotypes including both obstructive and restrictive phenotypes as detected by pulmonary function testing (PFTs), and has advanced the understanding of current clinical guidelines1-5. From the initial classification of chronic lung allograft rejection based primarily on pulmonary function testing, clinical guidelines now encompass CLAD phenotypes, presumed causes, characteristic imaging findings, and refinement of histopathological grades.
Abstract Ceftolozane-tazobactam (C/T) pharmacokinetics during extracorporeal membrane oxygenation (ECMO) has not been previously studied. In this work we report on the C/T plasmatic levels in a lung transplant (LTX) recipient during ECMO, treated with C/T (i.v., 2 g ceftolozane and 1 g tazobactam, every 8 hours]) for a Pseudomonas aeruginosa pulmonary infection. PMID: 30642936 [PubMed - as supplied by publisher]
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"For your eyes only": ophthalmic complications following lung transplantation. J Thorac Dis. 2018 Nov;10(11):6285-6297 Authors: Dhal U, Raju S, Singh AD, Mehta AC Abstract Ophthalmic complications in the lung transplant population are a little-known entity. It includes a spectrum of diseases ranging from infections such as cytomegalovirus (CMV) retinitis, herpetic keratitis, Pseudallescheria boydii to non-infectious complications such as posterior subcapsular cataracts (PSCs), cyclosporine retinopathy, and post-transplant lymphoproliferative disorder (PTLD). These diseases can be attributed t...
Authors: Poggi C, Mantovani S, Pecoraro Y, Carillo C, Bassi M, D'Andrilli A, Anile M, Rendina EA, Venuta F, Diso D Abstract Chronic obstructive pulmonary disease (COPD) is the major causes of disability and mortality. The efficacy of maximal medical treatment, although effective at the early stages of the disease, becomes limited when extensive alveolar destruction is the main cause of respiratory failure. At this stage of the disease more aggressive options, when feasible, should be considered. Lung transplantation and lung volume reduction surgery (LVRS) are currently available for a selected group of patients. E...