A randomized phase III trial for alleviating radiation-induced xerostomia with chewing gum

Radiotherapy (RT) is an important treatment modality for head and neck cancer (HNC) located to the oral cavity and oropharynx. Irradiation of the parotid and submandibular glands, as well as minor salivary glands, is often inevitable without compromising tumor control. Radiation-induced xerostomia (the subjective feeling of dry mouth) and salivary gland hypofunction (objectively reduced salivary flow) is a severe morbidity for HNC survivors following curative intended RT [1].
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Original Article Source Type: research