Nilotinib Ameliorates Folic Acid-Induced Acute Kidney Injury Through Modulation of TWEAK and HSP-70 Pathways.

CONCLUSION: Anti-inflammatory, anti-apoptotic and anti-oxidant potentials are the main mechanisms by which nilotinib can ameliorate folic acid-induced AKI. Modulation of TWEAK and HSP 70 pathways are thought to be the main contributor to the observed ameliorative potential. PMID: 31593741 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31593741?dopt=Abstract

Source: Toxicology - October 4, 2019 Category: Toxicology Authors: Zaghloul MS, Abdelrahman RS Tags: Toxicology Source Type: research