The Toll Mounts From a Mystery Disease Some Call “The New Polio”

Carter Roberts’ motorized wheelchair didn’t arrive until the day he died. It had been a long time coming and his parents had fought hard to get it. The chair cost more than $32,000 and the insurance companies wouldn’t cover it, so the family went to court. One insurer eventually agreed to pay for some components of the chair but not the whole thing. And then none of it mattered anyway. On Sept. 22, 2018, the Roberts’ doorbell rang and the chair was delivered. Also on Sept. 22, 2018, Carter died, just three months shy of his sixth birthday. He had been largely paralyzed for the final two years of his life. The family is only now beginning to pick their way through the horror of what happened. “Our eight-year-old daughter believes she can speak to him,” says Carter’s mother Robin. “She was playing video games the other day and she’s looking up and going, ‘Carter are you seeing this? I need your help.’” By any measure, the Roberts family of Richmond, Va. was spectacularly unlucky. They lost their son to a disease that science first recognized only in 2012. It’s new enough that it didn’t even have a formally accepted name until 2014. When it got one, it was one of those names that is more or less just a clinical description of what the disease is: acute flaccid myelitis (AFM), a sudden inflammation of spinal tissue resulting in flaccid paralysis of the muscles of the limbs, neck, face and often d...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Infectious Disease viruses Source Type: news

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ConclusionsThis case series demonstrates that the use of a high frequency jet ventilator for cardiac MRI was feasible, safe, providing good quality cardiac imaging and avoiding anesthesia personnel to be inside the hazardous environment of MRI room. Future studies are needed to confirm its safety and efficiency in pediatric patients.ResumoJustificativa e objetivosA ressonância magnética (RM) cardíaca é uma técnica utilizada na avaliação de crianças com cardiopatias congênitas. A anestesia geral garante imobilidade, especialmente em pacientes não cooperador...
Source: Brazilian Journal of Anesthesiology - Category: Anesthesiology Source Type: research
Publication date: Available online 22 October 2019Source: Autoimmunity ReviewsAuthor(s): Daniel Blockmans, Raashid Luqmani, Lucia Spaggiari, Carlo SalvaraniAbstractWith advances in our understanding of the pathogenesis of large vessel vasculitides, we recognise the persistence of inflammation in large vessels, sometimes despite therapy to control clinical symptoms. Achieving an early diagnosis and establishing the extent of disease are important steps in improving our management of these diseases. Imaging is playing an increasing role in the assessment of these patients from diagnosis to prognosis. We review the current an...
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
Conclusion: The relative proportion of IPUD is increasing in our population in contrast to the drop of H. pylori-PUD. Treatment with high-dose PPI, and for a long duration, heals IPUD and protects from recurrence. PMID: 31630582 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
Conclusions: Patients with clinical signs of inflammation and acute PVT have a low risk of malignancy in contrast to patients without signs of inflammation and acute PVT, which have a high risk of oncologic or hemato-oncologic disease. Patients with negative hemato-oncologic screening should be carefully observed over time because we expect they are at higher risk for the development of hemato-oncologic disease, independent from the presence and number of procoagulation risk factors. PMID: 31630579 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
Conclusions: The results indicate that a possible mechanism behind an anastomotic leakage is an impaired circulation and thus insufficient saturation to the small intestine peroperatively. This develops into an inflammation both intraperitoneally and intravenously, which, if not reversed, spread within the gastrointestinal tract .The colorectal anastomosis is the most vulnerable part of the gastrointestinal tract postoperatively and hypoxia and inflammation may occur there, and an anastomosis leakage will be the consequence. PMID: 31630578 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
Authors: Company-Quiroga J, Alique-García S, Romero-Maté A Abstract Discoid lupus erythematosus is the most disfiguring and common presentation of chronic cutaneous lupus erythematosus. Although most patients will respond to lifestyle measures and topical treatment, a non-negligible number of patients will require systemic and physical therapy, either alone or in combination. We performed a review of the available evidence on the discoid lupus erythematosus treatment. Lifestyle measures and topical treatment (corticosteroids and topical calcineurin inhibitors) remain the therapeutic strategies with th...
Source: Clinical, Cosmetic and Investigational Dermatology - Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research
This study aims to examine the behavior of four different finishing and polishing systems on the roughness, gloss and morphology surface of one resin composite. METHODS: Twelve Filtek XTE Supreme (3M ESPE) discs were prepared and divided into 4 groups (n=3), depending on the different finishing and polishing systems: Group 1 (GP1) Sof-Lex Extra- Thin XT discs; Group 2 (GP2) Sof-Lex Coarse black disc, multi-fluted bur, Sof-Lex Diamond Polishing System Spirals; Group 3 (GP3) Sof-Lex Coarse black disc, multi-fluted bur, Sof-Lex Diamond Polishing System Spirals, Diamond Twist SCL; Group 4 (GP4) with Sof-Lex Coarse black di...
Source: Minerva Stomatologica - Category: Dentistry Tags: Minerva Stomatol Source Type: research
Publication date: Available online 21 October 2019Source: Materials Today: ProceedingsAuthor(s): P.G. Venkatakrishnan, V. KarthikAbstractThe electroless Ni-B alloy coatings are prepared using an alkaline plating bath with nickel chloride as the source of nickel ions and sodium borohydride as the reducing agent as well as the source of boron ions in presence of zinc acetate in the plating bath. The effect zinc acetate concentration on plating rate, chemical composition, surface morphology, structural characteristics, hardness and wear properties of the electroless Ni-B alloy coatings are evaluated. The boron content in the ...
Source: Materials Today: Proceedings - Category: Materials Science Source Type: research
Publication date: February 2020Source: Materials Science in Semiconductor Processing, Volume 106Author(s): M. Thiruppathi, K. Leeladevi, C. Ramalingan, Kuan-Chung Chen, E.R. NagarajanAbstractIn the past few years, the occurrence of pharmaceutical wastes into the environment increases in day-to-day and poses negative risks to the living organisms. In this work, we developed novel biochar supported copper tungstate nanocomposites (Bio-CuWO4 NCs) and utilized as a visible light active photocatalyst for the degradation of ciprofloxacin (CF) drug and electrocatalyst for the oxidation of methanol. The Bio-CuWO4 NCs were synthesi...
Source: Materials Science in Semiconductor Processing - Category: Materials Science Source Type: research
Publication date: Available online 21 October 2019Source: Materials Science and Engineering: CAuthor(s): Daniel de Castro Girão, Miloslav Béreš, André Luiz Jardini, Rubens Maciel Filho, Cleiton Carvalho Silva, Abner de Siervo, Hamilton Ferreira Gomes de Abreu, Walney Silva AraújoAbstractCoCrMo alloys have been used for several decades in implantable devices due to their favourable mechanical properties, low wear rate in addition to good biocompatibility and high corrosion resistance. These alloys are conventionally produced via casting and/or forging route, however additive manufacturing ...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
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