Rosai-Dorfman disease and Hodgkin lymphoma synchronously involving the same lymph node: A rare case report with review of literature

We report a patient with HL and RDD involving the same lymph node concurrently. Both the areas were confirmed by histomorphology and immunohistochemistry (IHC). The detection of RDD in lymphoma cases is incidental and seems to have no clinical significance. Thus, finding of focal RDD does not affect therapeutic decisions of these patients. However, admixture of lymphoma cell population (both HL and NHL) along with histiocytic proliferation can be a diagnostic challenge at times, especially in inexperienced hands and a resource-limited setup where IHC is not available.
Source: Current Medicine Research and Practice - Category: General Medicine Source Type: research