Postcolonoscopy Appendicitis: A Review of 57 Cases
The purpose of this study is to review the cases of postcolonoscopy appendicitis (PCA) reported in the literature. A comprehensive search using PubMed, EMBASE, Scopus, and Google Scholar identified 57 cases. The median age at presentations of PCA was 55 years. PCAs typically occurred during the first 24 hours after colonoscopy, and the majority developed after diagnostic colonoscopy. Clinical presentations were similar to those with common acute appendicitis, though with a high perforation rate. Most patients were correctly diagnosed using ultrasound or computed tomography scan. Treatment included open appendicectomy, laparoscopic appendicectomy or cecotomy, radiologic drainage of the abscess, nonoperative treatment with antibiotics. In addition to barotrauma, fecalith impaction into the appendiceal lumen, direct trauma to the appendiceal orifice, and underlying ulcerative colitis, a pre-existing subclinical disease of the appendix seems to play an important role in the pathogenesis. For PCA, timely diagnosis and management are crucial to attain a satisfactory outcome.
ConclusionsThe association of gene variants on risk of appendicitis and its severity suggest an etiologic role of genetically regulated inflammatory response. This may have implications for understanding the prognosis of untreated appendicitis as a possible self-limiting disorder and for understanding the inverse association of appendicitis with ulcerative colitis.
PMID: 31826282 [PubMed - in process]
PMID: 31639214 [PubMed - in process]
PMID: 31639212 [PubMed - in process]
PMID: 31639211 [PubMed - in process]
PMID: 31639201 [PubMed - in process]
In the first episode of Not Crazy or the final episode of A Bipolar, A Schizophrenic and a Podcast, Gabe and Michelle reminisce on past episodes, and Michelle tells us what her plans are for the future. Later, Michelle gives some words of wisdom to Gabe’s new co-host, Jackie Zimmerman. We get to know Jackie and discuss how Gabe and Jackie will be taking over BSP, but with a slightly new direction and a new name! Listen Now to get all the details. SUBSCRIBE &REVIEW About The Hosts Gabe Howard is an award-winning writer and speaker who lives with bipolar disorder. He is the author of the popular book, Mental Il...
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