Effect of Oral Contraceptive Pill and/or Metformin in PCOS Effect of Oral Contraceptive Pill and/or Metformin in PCOS

What benefits might these therapies offer to patients with PCOS? A new review examines the therapeutic impacts.Clinical Endocrinology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

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Publication date: Available online 18 October 2019Source: The Lancet Diabetes &EndocrinologyAuthor(s): Eleanor P Thong, Ethel Codner, Joop S E Laven, Helena TeedeSummaryReproductive dysfunction is a common but little studied complication of diabetes. The spectrum of reproductive health problems in diabetes is broad, and encompasses delayed puberty and menarche, menstrual cycle abnormalities, subfertility, adverse pregnancy outcomes, and potentially early menopause. Depending on the age at diagnosis of diabetes, reproductive problems can manifest early on in puberty, emerge later when fertility is desired, or occur duri...
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
In what ways might hyperinsulinemia and insulin resistance impact fertility outcomes in patients with PCOS?Clinical Endocrinology
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news
Publication date: Available online 20 September 2019Source: Molecular and Cellular EndocrinologyAuthor(s): Mariana Di Pietro, Candela Velazquez, María Eugenia Matzkin, Mónica Beatriz Frungieri, Mariana Gómez Peña, Ignacio de Zúñiga, Natalia Pascuali, Griselda Irusta, María Silvia Bianchi, Fernanda Parborell, Dalhia AbramovichAbstractMetformin (MET) is the most widely prescribed hypoglycemic drug in type 2 diabetes and Polycystic Ovary Syndrome. Besides its effects on glucose metabolism, MET exerts beneficial effects on these patients’ fertility. However, the exact mech...
Source: Molecular and Cellular Endocrinology - Category: Endocrinology Source Type: research
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): DONNA F. Vine, MAHUA Ghosh, KATERINA Maximova, SPENCER D. Proctor
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Jamie L. Benham, Jane E. Booth, Christine Friedenreich, Doreen M. Rabi, Ronald J. Sigal
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
AbstractPolycystic ovary syndrome (PCOS) affects 6 –15% of women of reproductive age. Nonalcoholic fatty liver disease (NAFLD) affects 25–30% of the general population and its prevalence increases in parallel with the epidemics of obesity and type 2 diabetes mellitus. A growing body of evidence suggests that NAFLD and PCOS quite often co-exist. The aim of this article is to summarize and critically appraise the literature regarding: (1) the rates of co-existence of the two entities, (2) the possible pathophysiological links, (3) the proper diagnostic assessment and (4) the appropriate management of women with N...
Source: Endocrine - Category: Endocrinology Source Type: research
Authors: Carvalho LML, Dos Reis FM, Candido AL, Nunes FFC, Ferreira CN, Gomes KB Abstract Polycystic Ovary Syndrome (PCOS) is characterized by hyperandrogenism, amenorrhea, and polycystic ovaries. This endocrinopathy is associated with many metabolic disorders such as dyslipidemia and insulin resistance, with increased risk of type 2 diabetes mellitus, metabolic syndrome, and cardiovascular complications. Inflammation is likely to play an important role in the promoting these metabolic imbalances, while prothrombotic and pro-oxidative mechanisms further contribute to the cardiovascular risk of these patients. The e...
Source: Endocrine Regulations - Category: Endocrinology Tags: Endocr Regul Source Type: research
Authors: Pasquali R, Oriolo C Abstract Androgen excess is often associated with obesity states, at any age of life, because of changes in the pattern of secretion or metabolism of androgens and in their actions at the level of target tissues, particularly the adipose tissue. Androgen excess plays an important role in favouring the expansion of visceral fat, which characterize so-called visceral obesity. Moreover, there is evidence that the combination of androgen excess and obesity may favour the development of metabolic disorders, such as the metabolic syndrome and type 2 diabetes. In obese adolescent girls, andro...
Source: Frontiers of Hormone Research - Category: Endocrinology Tags: Front Horm Res Source Type: research
Publication date: Available online 6 September 2019Source: The Lancet Diabetes &EndocrinologyAuthor(s): The Lancet Diabetes &Endocrinology
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
In recognition of Polycystic Ovary Syndrome (PCOS) Awareness Month, Flo, a digital platform for women’s health and wellbeing, has announced the successful launch of PCOS Health Assistant, a self-assessment tool to help identify the risk of PCOS...
Source: Medgadget - Category: Medical Devices Authors: Tags: Ob/Gyn Source Type: blogs
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