Glucocorticoid receptor activation stimulates the Na-Cl co-transporter and influences the diurnal rhythm of its phosphorylation.

This study has implications for circadian BP homeostasis, particularly in individuals with abnormal glucocorticoid signaling as is found in chronic stress and corticosteroid therapy.
PMID: 31588796 [PubMed - as supplied by publisher]

Source: American Journal of Physiology. Renal Physiology - October 6, 2019 Category: Physiology Authors: Ivy JR, Jones NK, Costello HM, Mansley MK, Peltz TS, Flatman PW, Bailey MA Tags: Am J Physiol Renal Physiol Source Type: research