Task-based fMRI predicts response and remission to exposure therapy in obsessive-compulsive disorder [Psychological and Cognitive Sciences]

Exposure and ritual prevention (EX/RP) is an effective first-line treatment for obsessive-compulsive disorder (OCD), but only some patients achieve minimal symptoms following EX/RP. Herein, we investigate whether task-based neural activity can predict who responds best to EX/RP. Unmedicated adult patients with OCD (n = 36) and healthy participants (n =...

Source: Proceedings of the National Academy of Sciences - October 7, 2019 Category: Science Authors: David Pagliaccio, Rachel Middleton, Dianne Hezel, Shari Steinman, Ivar Snorrason, Marina Gershkovich, Raphael Campeas, Anthony Pinto, Page Van Meter, H. Blair Simpson, Rachel Marsh Tags: PNAS Plus Source Type: research