1,306 U.S. infants were born with syphilis in 2018, even though it's easy to prevent

1,306 U.S. infants were born with syphilis in 2018, even though the disease is easy to prevent. 78 of those babies were stillborn, and 16 died after birth.
Source: Los Angeles Times - Science - Category: Science Authors: Source Type: news

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Syphilis has been associated with an increase in HIV RNA and a temporary decline in CD4 T cell counts in people living with HIV who are not receiving antiretroviral treatment (ART), and may be associated with ...
Source: BMC Infectious Diseases - Category: Infectious Diseases Authors: Tags: Case report Source Type: research
by Amin Addetia, Lauren C. Tantalo, Michelle J. Lin, Hong Xie, Meei-Li Huang, Christina M. Marra, Alexander L. Greninger Developing a vaccine againstTreponema pallidum subspeciespallidum, the causative agent of syphilis, remains a public health priority. Syphilis vaccine design efforts have been complicated by lack of an in vitroT.pallidum culture system, prolific antigenic variation in outer membrane protein TprK, and lack of functional annotation for nearly half of the genes. Understanding the genetic basis ofT.pallidum reinfection can provide insights into variation among strains that escape cross-protective immunity. ...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
We present herein a case of syphilide psoriasiforme, an uncommon but well recognized clinical presentation of secondary syphilis. A 46-year-old HIV-infected female patient was referred to our attention with a presumptive diagnosis of palmoplantar psoriasis. On examination, there were exuberant pinkish-red papules and plaques covered with a thick silvery scale in the palms, flexor surfaces of the wrists, and the medial longitudinal arches of the feet. Serological and histopathological analyses uncovered the diagnosis of syphilis. Clinical remission was obtained after treatment. A detailed review of the literature on syphili...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - Category: Tropical Medicine Authors: Tags: Rev Inst Med Trop Sao Paulo Source Type: research
;n JM Abstract The aim of study was to assess the prevalence of Treponema pallidum and HIV infection in Amerindian people (Mbya Guarani) over the age of 11 in Puerto Iguazu (Argentina) and to describe the contact tracking of cases. The method was a cross-sectional study in the Mbya Guarani people living in three villages of Puerto Iguazu (community A, pop. 1,146; community B, pop. 369; and community C, pop. 149). Participants were randomly invited to participate in the survey and in blood testing. Of the 551 participants, 48 were infected by T. pallidum (8.71%; 95% confidence interval [CI] 7.38-10.04). The infecti...
Source: Revista do Instituto de Medicina Tropical de Sao Paulo - Category: Tropical Medicine Authors: Tags: Rev Inst Med Trop Sao Paulo Source Type: research
ConclusionsSyphilitic outer retinopathy affected the retinal structures and function that can be restored by antibiotic treatments.
Source: Documenta Ophthalmologica - Category: Opthalmology Source Type: research
Publication date: Available online 2 April 2020Source: Actas Dermo-Sifiliográficas (English Edition)Author(s): J. Granizo-Rubio, C. Caviedes-Vallejo, N. Chávez-Dávila, V. Pinos-León
Source: Actas Dermo-Sifiliograficas - Category: Dermatology Source Type: research
Publication date: Available online 1 April 2020Source: Antiviral ResearchAuthor(s): Jieqiong Ma, Yanan Ren, Lin He, Xiaoxia He, Xing Wenge, Jiang Yan
Source: Antiviral Therapy - Category: Virology Source Type: research
HIGHLIGHTS Adolescents and young adults are particularly susceptible to sexually transmitted infections (STIs), and cases of chlamydia, gonorrhea and syphilis have been rapidly increasing among young people in recent years. Young people face multiple roadblocks to obtaining high-quality sexual health inform ation and STI care that can help them avoid STIs or mitigate the effects of an infection. Advocates and policymakers addressing STIs among young people should support the needs of those most vulnerable to STIs through high-quality sex education programs, access to clinical care, preventive technolo gies and vaccines,...
Source: The Guttmacher Institute - Category: International Medicine & Public Health Authors: Source Type: news
Abstract Congenital infections refer to a group of perinatal infections that may have similar clinical presentations, including rash and ocular findings. TORCH is the acronym that covers these infections (toxoplasmosis, other [syphilis], rubella, cytomegalovirus, herpes simplex virus). There are, however, other important causes of intrauterine/perinatal infections, including enteroviruses, varicella zoster virus, Zika virus, and parvovirus B19. Intrauterine and perinatal infections are significant causes of fetal and neonatal mortality and important contributors to childhood morbidity. A high index of suspicion fo...
Source: Hong Kong Med J - Category: General Medicine Authors: Tags: Hong Kong Med J Source Type: research
AbstractSyphilis and HIV among gay, bisexual and other men who have sex with men (MSM) are syndemic suggesting current prevention strategies are not effective. Sex partner meeting places and their networks may yield effective and optimal interventions. From 2009 to 2017, 57 unique venues were reported by  >  1 MSM and 7.0% (n = 4), 21.1% (n = 12) and 71.9% (n = 41) were classified as syphilis, HIV or co-diagnosed venues, respectively. Forty-nine venues were connected in one main network component with four online, co-diagnosis venues representing 51.6% of reports a...
Source: AIDS and Behavior - Category: Infectious Diseases Source Type: research
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