Vitamin B12 deficiency: The six major signs you could have pernicious anaemia

VITAMIN B12 is a nutrient found in some foods and being deficient in the vitamin is a worldwide problem. Pernicious anaemia is a condition which the body can ’t make enough healthy red blood cells because it doesn’t have enough vitamin B12. What are the six signs you may have pernicious anaemia?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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This study assessed whether the AG patients with vitamin B12 deficiency (B12D/AG patients) had significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity than healthy control subjects.MethodsThe blood hemoglobin (Hb) and serum iron, vitamin B12, folic acid, homocysteine, and GPCA levels in 56 B12D/AG patients and 532 healthy control subjects were measured and compared.ResultsWe found that 56 B12D/AG patients had significantly lower mean blood Hb and serum iron levels as well as significantly higher mean corpuscular volume (MCV) and me...
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
The unnamed 64-year-old was seen by doctors in Singapore. The man was diagnosed with pernicious anaemia, where a person has low levels of red blood cells due to a deficiency in vitamin B12.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
This study assessed whether all AG patients with iron deficiency (so-called ID/AG patients) had iron deficiency anemia (IDA) and evaluated whether the ID/AG patients had significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity than healthy control subjects.MethodsThe blood hemoglobin (Hb) and serum iron, vitamin B12, folic acid, homocysteine, and GPCA levels in 180 ID/AG patients and 532 healthy control subjects were measured and compared.ResultsWe found that 180 ID/AG patients had significantly lower mean corpuscular volume (MCV) a...
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
This study assessed whether all AG patients with iron deficiency (so-called ID/AG patients) had iron deficiency anemia (IDA) and evaluated whether the ID/AG patients had significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity than healthy control subjects. METHODS: The blood hemoglobin (Hb) and serum iron, vitamin B12, folic acid, homocysteine, and GPCA levels in 180 ID/AG patients and 532 healthy control subjects were measured and compared. RESULTS: We found that 180 ID/AG patients had significantly lower mean corpuscula...
Source: J Formos Med Assoc - Category: General Medicine Authors: Tags: J Formos Med Assoc Source Type: research
VITAMIN B12 is the water-soluble vitamin that plays an essential role in the production of red blood cells. Lacking in the vitamin could cause a number of signs in the body. What are the five main symptoms that could mean you have pernicious anaemia?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
VITAMIN B12 deficiency is a common condition that could manifest to neurological and even psychiatric disorders. A worrying cause of the vitamin deficiency could cause pernicious anaemia. These are the five warning signs you could be developing the condition.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
We report a 5-month old exclusively breastfed full-term infant with emesis, lethargy, progressive pancytopenia, hemolysis, hypofibrinogenemia, elevated lactate dehydrogenase and a hypercellular bone marrow with dyserythropoiesis. The B12 level in the serum was undetectable. The infant’s lethargy resolved within 48 hours of intramuscular B12 injection, followed by rapid improvement of pancytopenia. The asymptomatic mother had a normal hemoglobin and mean corpuscular volume, but undetectable B12 level and positive antibodies to intrinsic factor, consistent with pernicious anemia masked by folate supplementation in the ...
Source: Journal of Pediatric Hematology Oncology - Category: Hematology Tags: Online Articles: Clinical and Laboratory Observations Source Type: research
ABSTRACTIn 1998 a Tolerable Upper Intake Level (UL) for folic acid was established based on case reports from the 1940s suggesting that high-dosage folic acid intake, used to treat patients with pernicious anemia, had the potential to precipitate or speed-up the development of neurological problems. This UL has been employed in the decision-making process used by more than 80 countries to establish programs to fortify staple foods with folic acid to prevent neural tube birth defects. Some have claimed that this UL is flawed and has become an obstacle to the wider adoption of neural tube defect prevention programs and have ...
Source: American Journal of Clinical Nutrition - Category: Nutrition Source Type: research
Abstract In 1998 a Tolerable Upper Intake Level (UL) for folic acid was established based on case reports from the 1940s suggesting that high-dosage folic acid intake, used to treat patients with pernicious anemia, had the potential to precipitate or speed-up the development of neurological problems. This UL has been employed in the decision-making process used by more than 80 countries to establish programs to fortify staple foods with folic acid to prevent neural tube birth defects. Some have claimed that this UL is flawed and has become an obstacle to the wider adoption of neural tube defect prevention programs...
Source: The American Journal of Clinical Nutrition - Category: Nutrition Authors: Tags: Am J Clin Nutr Source Type: research
VITAMIN B12 deficiency symptoms can occur if you lack vitamin B12-rich foods in your diet, but they could also be triggered by pernicious anaemia. Here are six signs of the condition to look out for.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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