Index of Plantar Pressure Alters with Prolonged Diabetes Duration

AbstractIntroductionDiabetic foot ulcers develop with deviations in the distribution of plantar pressure. It is difficult to interpret any alteration in plantar pressure under different conditions of type 2 diabetes mellitus (T2DM). The aim of this study was to gain a better insight into the variations in plantar pressure with increased duration of diabetes.MethodsPlantar pressure was examined in 1196 participants with or without T2DM. Subjects with normal glucose tolerance (NGT) and impaired glucose tolerance (IGT) were assigned to control groups, and those with T2DM were divided into five groups according to diabetes duration ( 15  years). The clinical characteristics, plantar peak pressure, and pressure–time integral (PTI) were compared among the seven study groups, and factors associated with peak pressure and the PTI were analyzed.ResultsAt the hallux, peak pressure exhibited an upward trend in patients with T2DM within 5  years of diabetes duration, followed by a distinct downward slope with further progression of the disease (trend analysis,p  
Source: Diabetes Therapy - Category: Endocrinology Source Type: research

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Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Purpose of review The current review addresses one of the most common neurological disorders, diabetic polyneuropathy (DPN). DPN is debilitating, irreversible and dwarfs the prevalence of most other chronic disorders of the nervous system. Its complications include foot ulceration, amputation, falling and intractable neuropathic pain. Moreover, tight control of hyperglycemia reduces the incidence of DPN in type 1 diabetes mellitus but its role in type 2 diabetes mellitus is less clear. Recent findings New therapeutic options to reverse the development of DPN or its associated pain have been proposed but none have sign...
Source: Current Opinion in Neurology - Category: Neurology Tags: PERIPHERAL NERVE AND NEURO-MUSCULAR JUNCTION DISEASE: Edited by Mary M. Reilly Source Type: research
Publication date: Available online 28 June 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Lei Xu, Hui Zeng, Jun Zhao, Jungong Zhao, Jun Yin, Hua Chen, Yimin Chai, Yuqian Bao, Fang Liu, Weiping JiaAbstractBackgroundDiabetic foot ulcers developed with the deviation of plantar pressure. It is difficult to interpret the alteration of plantar pressure under different conditions of type 2 diabetes mellitus. This work aims to gain a better insight into the variation of plantar pressure as diabetes duration prolongs.MethodsPlantar pressure was examined among 1,196 participants with or withou...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Conclusion In conclusion, this study highlighted high re-intervention, re-amputation and new ulceration rates. Strategies to improves these outcomes in such high-risk patients are warranted. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Experimental and Clinical Endocrinology and Diabetes - Category: Endocrinology Authors: Tags: Article Source Type: research
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Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
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Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
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Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
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