Medical News Today: Deep brain stimulation can be effective for severe depression

A study that gathered data for at least 8 years has shown that deep brain stimulation can have a robust, sustained effect in people with severe depression.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Depression Source Type: news

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In this study, AT1-AAs were detected in the sera of patients with peripheral arterial disease (PAD) and the positive rate was 44.44% vs. 17.46% in non-PAD volunteers. In addition, analysis showed that AT1-AAs level was positively correlated with PAD. To reveal the causal relationship between AT1-AAs and vascular aging, an AT1-AAs-positive rat model was established by active immunization. The carotid pulse wave velocity was higher, and the aortic endothelium-dependent vasodilatation was attenuated significantly in the immunized rats. Morphological staining showed thickening of the aortic wall. Histological examination showe...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusions: In>8 years of observation, most participants experienced a robust and sustained antidepressant response to SCC DBS. News in Context: Ethical issues raised around deep brain stimulation (DBS) research Closing the Circuit: Helen Mayberg’s research could revolutionize depression treatment Expo Day: Neuroenginnering, BPI, Arrowsmith Program &ARPF from SharpBrains
Source: SharpBrains - Category: Neuroscience Authors: Tags: Cognitive Neuroscience Health & Wellness Technology antidepressant area-25 brain pacemaker brain stimulation DBS deep-brain-stimulation depression Helen-Mayberg neurosurgical treatment Source Type: blogs
Deep brain stimulation (DBS) of a region called the subcallosal cingulate appears to be safe and effective at reducing symptoms of depression in patients with treatment-resistant depression over time, according to asmall study inAJP in Advance.Previous studies suggest that up to one-third of all patients with major depression have treatment-resistant depression (that is, they fail to experience symptom improvements during two or more antidepressant trials). “Given that patients with treatment-resistant depression are highly susceptible to recurrent depressive episodes, the ability of DBS or any treatment to support l...
Source: Psychiatr News - Category: Psychiatry Tags: ajp in advance Andrea Crowell bipolar disorder DBS deep brain stimulation functioning HAM-D subcallosal cingulate surgery treatment-resistant depression Source Type: research
The effects of the therapy in a small group of patients were long-lasting, researchers say, adding to evidence that the approach works for treatment-resistant depression.
Source: The Scientist - Category: Science Tags: News & Opinion Source Type: news
Authors: Gupta A, Khanna S, Jain R Abstract The main objective of this study is to assess the effectiveness of deep brain stimulation (DBS) of the ventral striatum (VS) of the anterior limb of internal capsule for patients suffering from refractory obsessive-compulsive disorder (OCD) and to compare its result with traditional anterior capsulotomy. The present study consisted of two patients subjected to stimulation of ventral capsule (VC)/VS region of internal capsule for refractory OCD. Leads were implanted on both sides stereotactically using fused images of magnetic resonance imaging and computed tomography scan...
Source: Indian Journal of Psychiatry - Category: Psychiatry Tags: Indian J Psychiatry Source Type: research
Our weekly round-up of the best psychology coverage from elsewhere on the web An MIT professor gave his students Fitbits to find out how exercise affected their academic performance — but instead stumbled upon some interesting insights into sleep, Jamie Ducharme at Time reports. Students who stuck to a consistent sleep pattern throughout the week seemed to do better in class, the team found, while differences in sleep quality between men and women could explain why female students were getting higher grades. “I can’t rewind the past and make up for all of the bad experiences I have had. But I can use th...
Source: BPS RESEARCH DIGEST - Category: Psychiatry & Psychology Authors: Tags: Weekly links Source Type: blogs
American Journal of Psychiatry, Ahead of Print.
Source: American Journal of Psychiatry - Category: Psychiatry Authors: Source Type: research
Abstract Deep brain stimulation (DBS) is an effective tool for treatment-resistant depression, though it is still unclear which brain area to target in order to get robust results. While research suggests that the nucleus accumbens (NAc) plays an important role in depression, studies using NAc DBS to improve depressive behavior have not been able to fully explain underlying molecular mechanisms. We therefore used unilateral high frequency stimulation of the NAc shell in rats to verify its effectiveness in treating depression and study involved neurotransmitter systems. Animals underwent social isolation and food d...
Source: Behavioural Brain Research - Category: Neurology Authors: Tags: Behav Brain Res Source Type: research
CONCLUSIONS: In>8 years of observation, most participants experienced a robust and sustained antidepressant response to SCC DBS. PMID: 31581800 [PubMed - as supplied by publisher]
Source: The American Journal of Psychiatry - Category: Psychiatry Authors: Tags: Am J Psychiatry Source Type: research
Under certain parameters, 3-tesla MRI scans can be performed safely on patients...Read more on AuntMinnie.comRelated Reading: FDA OKs Boston Scientific's MRI-conditional DBS device FDA issues proposals to improve MRI safety fMRI locates brain region tied to sleep-related depression FDA clears Medtronic brain stimulation for MR use New high-res 3D MRI map aids surgeons
Source: Headlines - Category: Radiology Source Type: news
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