Common genetic disease linked to father's age (EurekAlert, 6 June 2013)

A US study of the genetic disease Noonan Syndrome published in The American Journal of Human Genetics suggests that the de novo paternal mutation in the spermatogonial sperm cell may convey an advantage that allows them to increase in frequency, producing more mutated sperm in an age-dependent manner. The authors suggest that this may also confer a selection advantage for the recurrent mutations in the receptor tyrosine kinases that cause Apert syndrome and MEN2B. Full article

http://www.endocrinology.org/news/article.aspx?articleid= 6526

Source: Society for Endocrinology - June 10, 2013 Category: Endocrinology Source Type: news