DNA hypermethylation of Fgf16 and Tbx22 associated with cleft palate during palatal fusion

Conclusions: Taken together, these results suggest that hypermethylation of Fgf16 and Tbx22 is associated with decreased gene expression, which might be responsible for developmental failure of palatal fusion, eventually resulting in the formation of CP.
Source: Journal of Applied Oral Science - Category: Dentistry Source Type: research