Relief for Children ’s Migraine Headaches

New guidelines for therapies for children and adolescents can reduce or eliminate attacks of migraine and greatly shorten their duration.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Headaches Migraine Headaches Children and Childhood Drugs (Pharmaceuticals) Brain Source Type: news

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Pharmacogenomics, Ahead of Print.
Source: Future Medicine: Pharmacogenomics - Category: Genetics & Stem Cells Authors: Source Type: research
AbstractFremanezumab (fremanezumab-vfrm; Ajovy®), a monoclonal antibody that targets calcitonin gene-related peptide (CGRP), is indicated for the prevention of migraine in adults in the EU and USA. Subcutaneous fremanezumab 225  mg once monthly or 675 mg once every 3 months was effective in reducing monthly migraine days or headache days in patients with episodic or chronic migraine in pivotal, 12-week clinical trials. Both regimens also reduce acute headache medication use and headache-related disability. Improvements were maintained through ≤ 52 weeks of additional treatment in a longer-...
Source: Drugs and Therapy Perspectives - Category: Drugs & Pharmacology Source Type: research
AbstractChronic migraine (CM) is a leading cause of disability, worldwide. Research examining the systemic effects of CM is scant. Specifically, little is understood about the effects of migraine on CM patients ’ partners. Furthermore, the relational experiences of couples who deal with CM has been largely unexplored. Coming to better understand the systemic effects of migraine on couple relationships could enable more holistic biopsychosocial care for CM patients and their families. We utilized a phenom enological approach to study the CM experience in the context of couple relationships. We conducted dyadic intervi...
Source: Contemporary Family Therapy - Category: Psychiatry & Psychology Source Type: research
Authors: Chimed-Ochir O, Mine Y, Fujino Y Abstract OBJECTIVES: The current research aimed to study the relationship between health-related quality of life (poor perceived health/unhealthy days) and workers' pain. METHODS: This cross-sectional study was conducted among 1360 Japanese workers of a Japanese company in Kyushu. Health-related quality of life was measured by HRQOL-4 tool developed by Centers for Disease Control and Prevention of the USA. Pain was assessed by numeric rating scale with 0-10 points. Regression analysis was conducted to identify the relationship between health-related quality of life and ...
Source: Journal of Occupational Health - Category: Occupational Health Tags: J Occup Health Source Type: research
 Psychiatric medications are the religion and politics of the mental health advocacy world — don’t bring them up unless you want a fight to break out. Luckily, here at Not Crazy, we don’t shy away from confrontation.  In this episode, we cover the good, the bad, and the ugly surrounding medications. Like whether or not you should take them. We tackle side effects like feeling numb and sexual dysfunction and share our personal histories with medication therapy. Listen now! (Transcript Available Below) SUBSCRIBE &REVIEW About The Not Crazy Podcast Hosts Gabe Howard is an award-winning wri...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Antidepressant Antipsychotic General Medications Mental Health and Wellness Not Crazy Podcast Psychology Research Sexuality Stimulants Treatment Source Type: blogs
ConclusionWe found that there is a lack of high-quality evidence-based studies on the pharmacological treatment of PTH. Future studies are highly needed and must emphasize open-label studies with rigorous methodology or RCTs with a placebo-controlled design.
Source: The Journal of Headache and Pain - Category: Neurology Source Type: research
im Saurabh Chatterjee Gulf War illness (GWI) is characterized by the persistence of inflammatory bowel disease, chronic fatigue, neuroinflammation, headache, cognitive impairment, and other medically unexplained conditions. Results using a murine model show that enteric viral populations especially bacteriophages were altered in GWI. The increased viral richness and alpha diversity correlated positively with gut bacterial dysbiosis and proinflammatory cytokines. Altered virome signature in GWI mice also had a concomitant weakening of intestinal epithelial tight junctions with a significant increase in Claudin-2 prote...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Authors: Sánchez Ruiz P, Martín Villaescusa C, Duat Rodríguez A, Cantarín Extremera V, Ruiz-Falcó Rojas ML Abstract Primary trochlear headache is a little-known cause of periorbital headache described in adults. It can involve very disabling pain. In addition, it can be associated with other types of headaches, making them even more difficult to identify. To diagnose this pathology, it is necessary that the examination of the trochlea be incorporated into the usual clinical practice of the patient with headache, which will allow the establishment of an adequate treatment. The case...
Source: Archivos de la Sociedad Espanola de Oftalmologia - Category: Opthalmology Tags: Arch Soc Esp Oftalmol Source Type: research
by Craig Klugman, Ph.D. The Resident (Season 3; Episode 4): Hubris and Assault; New Amsterdam (Season 2; Episode 4): Taking medicine to the streets, assisted suicide, lead poisoning The Resident (Season 3; Episode 4): Hubris and Assault Hades is a social media white supremacist celebrity comes in with a headache and a history of brain arteriovenous malformation (AVM). He says he does not want Pravesh (Indian), Nevins (female), or Feldman (Jewish) touching him. Cain (African-American) offers to do his surgery even though the patient is a violent racist.…
Source: blog.bioethics.net - Category: Medical Ethics Authors: Tags: BioethicsTV Featured Posts Source Type: blogs
We report the case of a 9-year-old girl with linear scleroderma en coup de sabre (LSCS) who developed progressive white matter involvement, presenting as intractable hemiplegic migraine-like attacks induced by exercise. After a period of severely aggressive course, clinical and radiological stabilization was achieved under immunosuppressant treatment. Intrathecal synthesis of IgG and lymphocytic pleocytosis provided indirect evidence of a chronic inflammatory process of the central nervous system. We discuss the possible immunopathogenic mechanisms responsible for the neurocutaneous involvement in LSCS, favouring the hypot...
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
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