65.3 social behavior correlates of asd in fragile x syndrome
Fragile X syndrome (FXS) is the most common known cause of single gene ASD found in up to 60 percent of boys with FXS. Individuals with this neurodevelopmental disorder also have lifelong intellectual disability and social anxiety (SA). This lecture presents results on social behavior determinants of ASD status in FXS.
Hi all, I'm an MS3 that has wanted to be an ER doc since he was a kid. I have stayed away from sdn largely because I find it to be unnecessarily anxiety producing and toxic, especially in premedical and med student forums. In thinking about residency applications I ventured on here. What I have found, not surprisingly given my other experiences on this site, is waves of negativity, regret, frustration, and unhappiness written by emergency medicine physicians. I don't want to minimize what... Is there anything good about EM?
For anyone interested: https://psyarxiv.com/bhyg9/ Apparently, BA does not beat out active control. I am sure the common factors folks will love this. However, I caution that camp not to conflate studies of depression and anxiety with more severe problems.
The aim of this study was to review emerging evidence of novel treatments for anxiety disorders. We searched PubMed and EMBASE for evidence-based therapeutic alternatives for anxiety disorders in adults, covering the past five years. Eligible articles were systematic reviews (with or without meta-analysis), which evaluated treatment effectiveness of either nonbiological or biological interventions for anxiety disorders. Retrieved articles were summarized as an overview. We assessed methods, quality of evidence, and risk of bias of the articles. Nineteen systematic reviews provided information on almost 88 thousand particip...
In recent years, I’ve encountered a growing number of parents in my therapy practice who come to me fearing that their child has oppositional defiant disorder (ODD). According to the American Psychiatric Association, the primary signs of ODD are angry and irritable mood, argumentative and defiant behavior, and vindictiveness. Often these parents will share that a teacher or doctor told them their child may have ODD, and that when they looked up the condition online, they recognized some of the symptoms in their child’s behavior. As a parent myself, the worry and confusion on my clients’ faces and, in the...
An Olympic-caliber competitor herself, Yetsa Tuakli-Wosornu ’01 works to heal and empower disabled athletes in her practice and at Yale’s Sports Equity Lab.
Disability is “frequently seen as being low down on the pecking order” when it comes to addressing inclusion and diversity, according to Adrian Ward, senior disability consultant for the Business Disability Forum.
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Conclusions: This study provides guidance for future mindfulness-based interventions to alleviate maternal stress in mothers of children with FXS.
This study investigates whether a newly discovered STEP inhibitor (TC-2153) could attenuate the behavioral and synaptic abnormalities in Fmr1 KO mice. TC-2153 reversed audiogenic seizure incidences, reduced hyperactivity, normalized anxiety states, and increased sociability in Fmr1 KO mice. Moreover, TC-2153 reduced dendritic spine density and improved synaptic aberrations in Fmr1 KO neuronal cultures as well as in vivo. TC-2153 also reversed the mGluR-mediated exaggerated LTD in brain slices derived from Fmr1 KO mice. These studies suggest that STEP inhibition may have therapeutic benefit in FXS. PMID: 28943283 [PubM...