27.1 neural structure is independently predicted by deprivation and threat in early  childhood

The impact of childhood adversity on risk for psychopathology is commonly examined using a cumulative risk model. In a recently proposed alternative approach, the dimensional model of adversity and psychopathology (DMAP), different dimensions of adversity are hypothesized to impact health and well-being through different neural pathways. We expect deprivation to impact thickness in areas of cortex involved in higher-order cognition such as the prefrontal cortex. In contrast, we expect threat to selectively impact subcortical structures associated with increased reactivity to emotional stimuli.

Source: Journal of the American Academy of Child and Adolescent Psychiatry - September 30, 2019 Category: Psychiatry Authors: Margaret A. Sheridan, William E. Copeland, Laura S. Machlin, Cheryl R. Stein, Kimberly L.H. Carpenter, Helen L. Egger Source Type: research