Are you ready for the next big pandemic? International watchdog organization warns it could claim 80 million lives

(Natural News) Just over 100 years ago, in 1918, 500 million people across the globe contracted the Spanish flu in the deadliest pandemic in recorded history. Between 20 and 50 million of those infected died, including around 675,000 Americans. After first appearing in the United States, Europe and Asia, the disease spread like wildfire, eventually...
Source: - Category: Consumer Health News Source Type: news

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A recent study in this journal compared codon usage among NA subtypes (N1, N2, N6, and N8)  of H5Nx highly pathogenic avian influenza A viruses (HPAIVs) and suggested that codon usage in N1 subtype is better adapted to its host than the epidemic NA subtypes (N6 and N8), which had fewer number of human cases compared to the N1 subtype.1 To date, there are 18 known HA subtypes (H1-H18) and 11 known NA subtypes (N1-N11)2. However, only N1 and N2 subtypes have been reported to cause pandemics (H1N1 for the 1918 and 2009 pandemics; H2N2 for the 1957 pandemic; and H3N2 for the 1968 pandemic) or seasonal outbreaks in humans3.
Source: Journal of Infection - Category: Infectious Diseases Authors: Tags: Letter to the Editor Source Type: research
When high schoolers in New York City were curious whether the sushi in their local market contained the kind of fish that was advertised, GenBank held the clues. When historians wanted to identify the sequence of the lethal pandemic 1918 influenza virus that killed millions worldwide, they found the answer through GenBank. When physicians were…
Source: NLM In Focus - Category: Databases & Libraries Authors: Tags: Programs & Services Source Type: blogs
Publication date: Available online 30 September 2019Source: The Lancet Respiratory MedicineAuthor(s): Richard T Davey, Eduardo Fernández-Cruz, Norman Markowitz, Sarah Pett, Abdel G Babiker, Deborah Wentworth, Surender Khurana, Nicole Engen, Fred Gordin, Mamta K Jain, Virginia Kan, Mark N Polizzotto, Paul Riska, Kiat Ruxrungtham, Zelalem Temesgen, Jens Lundgren, John H Beigel, H Clifford Lane, James D Neaton, Richard T DaveySummaryBackgroundSince the 1918 influenza pandemic, non-randomised studies and small clinical trials have suggested that convalescent plasma or anti-influenza hyperimmune intravenous immunoglobuli...
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
Influenza infection is considered to be a serious respiratory disease in human. Annually, epidemics or even pandemics give rise to the frequent antigenetic variations of virus surface receptors, throughout the world. Bacterial infections followed by influenza are the biggest medical concerns associated with elevated mortality rates. These high morbidity and mortality rates, have become a priority in terms of health. Likewise, economic aspects of the issue have special importance also. In the present study, several articles have been investigated with regards to main key words including influenza A, secondary bacterial inf...
Source: Reviews in Medical Microbiology - Category: Microbiology Tags: VIROLOGY Source Type: research
The event kicks off “Spit Spreads Death,” an exhibition about this city’s health disaster and the worldwide influenza pandemic nearly a hundred years ago.
Source: Washington Post: To Your Health - Category: Consumer Health News Authors: Source Type: news
Abstract It remains uncertain why most infectious disease mortalities disappeared before modern medical interventions. Historical epidemiology using prospectively collected U.S. Army data from the Civil War (1860-1861), Spanish-American War (1898-1899), and First World War (1917-1918) suggests that epidemiological isolation was a major mortality risk factor for soldiers. Morbidity and mortality due to common infections decreased progressively from 1860 to 1918, except for influenza during the 1918 pandemic. Adult measles or mumps infections are indicative of isolated rural populations and correlated with disease m...
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
by Alexander D. Becker, Amy Wesolowski, Ottar N. Bj ørnstad, Bryan T. Grenfell A key question in ecology is the relative impact of internal nonlinear dynamics and external perturbations on the long-term trajectories of natural systems. Measles has been analyzed extensively as a paradigm for consumer-resource dynamics due to the oscillatory nature of the host-pathogen life cy cle, the abundance of rich data to test theory, and public health relevance. The dynamics of measles in London, in particular, has acted as a prototypical test bed for such analysis using incidence data from the pre-vaccination era (1944–...
Source: PLoS Computational Biology - Category: Biology Authors: Source Type: research
AbstractA large literature has documented links between harmful early-life exposures and later-life health and socioeconomic deficits. These studies, however, have typically been unable to examine the possibility that these shocks are transmitted to the next generation. Our study uses representative survey data from the United States to trace the impacts ofin utero exposure to the 1918 influenza pandemic on the outcomes of the children and grandchildren of those affected. We find evidence of multigenerational effects on educational, economic, and health outcomes.
Source: Demography - Category: International Medicine & Public Health Source Type: research
The 2018–2019 period marks the centennial of the "Spanish" influenza pandemic, which caused at least 50 million deaths worldwide. The unprecedented nature of the pandemic’s sudden appearance and high fatality rate serve as a stark reminder of the threat influenza poses. Unusual features of the 1918–1919 pandemic, including age-specific mortality and the high frequency of severe pneumonias, are still not fully understood. Sequencing and reconstruction of the 1918 virus has allowed scientists to answer many questions about its origin and pathogenicity, although many questions remain. This Review s...
Source: Science Translational Medicine - Category: Biomedical Science Authors: Tags: Reviews Source Type: research
Craig A. Molgaard explores the origins, spread and impact of the deadly influenza pandemic of 1918 –1919, and how the outbreak intersected with the end of the First World War
Source: Significance - Category: Statistics Authors: Tags: In Detail Source Type: research
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