Wnt1 Promotes EAAT2 Expression and Mediates the Protective Effects of Astrocytes on Dopaminergic Cells in Parkinson's Disease.

Conclusion: Wnt1 promoted EAAT2 expression and mediated the cytoprotective effects of astrocytes on dopaminergic cells. NF-κB might be involved in the regulation of EAAT2 by Wnt1.
PMID: 31582965 [PubMed - in process]

Source: Neural Plasticity - October 6, 2019 Category: Neurology Authors: Wei L, Chen C, Ding L, Mo M, Zou J, Lu Z, Li H, Wu H, Dai Y, Xu P, Lu Z Tags: Neural Plast Source Type: research