Smelling Danger: Olfactory Stem Cells Control Immune Defense during Chronic Inflammation.
Smelling Danger: Olfactory Stem Cells Control Immune Defense during Chronic Inflammation.
Cell Stem Cell. 2019 Oct 03;25(4):449-451
Authors: Rustenhoven J, Kipnis J
Abstract
Neurogenesis is critical to continuously replacie olfactory neurons but is impaired during chronic inflammatory rhinosinusitis. In this issue of Cell Stem Cell, Chen et al. (2019) describe the inflammation-induced switching of olfactory stem cells from a regenerative phenotype to one participating in immune defense; this process contributes to deficient replacement of olfactory sensory neurons.
PMID: 31585089 [PubMed - in process]
Source: Cell Stem Cell - Category: Stem Cells Authors: Rustenhoven J, Kipnis J Tags: Cell Stem Cell Source Type: research