T2-highlighted U-fibres and rapid parenchymal volume loss in AESD: an under-recognised subtype of paediatric acute encephalopathy syndromes

We present three paediatric cases from a tertiary paediatric neurosciences centre in xxxxx with characteristic subcortical signal change, and furthermore, follow up imaging which in all 3 patients demonstrated a varying degree of cerebral atrophy. We recommend that children presenting with prolonged seizures should be considered for MR imaging ideally after 48 hours if clinically stable, and early MR imaging follow-up (at 2-3 months) be performed routinely in patients with AED to assess for presence and degree of parenchymal volume loss for prognostication and to start neuroprotective therapy.
Source: Journal of Neuroradiology - Category: Radiology Source Type: research