Supraglottic devices for airway management in awake craniotomy

Awake craniotomy is a unique technique utilized for mapping neuro and motor function during neurosurgical procedures close to eloquent brain tissue. Since active communication is required only during surgical manipulation of eloquent brain tissue and the patient is “sedated” during other parts of the procedure, different methods for anesthesia management have been explored. Furthermore, airway management ranges from spontaneous breathing to oro or nasotracheal intubation. Case reports have described the use of laryngeal masks (LMs) previously; however, its safety compared to tracheal intubation has not been assessed. We conducted a retrospective analysis of 30 patients that underwent awake craniotomy for tumor surgery to compare the feasibility and safety of different airway management strategies. Nasal fiberoptic intubation (FOI) was performed in 21 patients while 9 patients received LM for airway management. Ventilation, critical events, and perioperative complications were evaluated. Cannot intubate situation occurred in 4 cases reinserting the tube after awake phase, while no difficulties were described reinserting the LM (P 
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

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Condition:   Tumor, Brain Intervention:   Other: dMRI, fMRI and electrocorticography Sponsor:   Centre Hospitalier Universitaire de Nice Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Contributors : Timothy Phoenix ; Smruti PatelSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusDiffuse intrinsic pontine gliomas (DIPGs) are highly lethal childhood brain tumors. Their unique genetic makeup, pathological heterogeneity, and brainstem location all present challenges to treatment. Developing mouse models that accurately reflect each of these distinct features will be critical to advance our understanding of DIPG development, progression, and therapeutic resistance. The aim of this study was to generate new mouse models of DIPG, and characterize the role of specific oncogen...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
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Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
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Source: Progress in Neurobiology - Category: Neuroscience Source Type: research
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Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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Source: Pituitary - Category: Endocrinology Source Type: research
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Source: The Scientist - Category: Science Tags: News & Opinion Source Type: news
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Source: Current Oncology - Category: Cancer & Oncology Tags: Curr Oncol Source Type: research
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Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Exclusive: tiny particles produced by motor traffic can invade the brain and carry carcinogensNew research has linked air pollution nanoparticles to brain cancer for the first time.The ultra-fine particles (UFPs) are produced by fuel burning, particularly in diesel vehicles, and higher exposures significantly increase people ’s chances of getting the deadly cancer. Previous work has shown that nanoparticles can get into the brain and that they can carry carcinogenic chemicals.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Air pollution Environment Cancer research Health Medical research Science Society UK news Source Type: news
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