Role of Pattern Electroretinogram in Ocular Hypertension and Early Glaucoma

Purpose: To test whether pattern electroretinogram (PERG) can early detect retinal ganglion cells dysfunction in ocular hypertension. Design: Cross-sectional observational study. Participants: The study included 3 groups: control, primary open-angle glaucoma (POAG) and ocular hypertension (OHT) groups with 30 eyes in each group. Materials and Methods: Visual fields were examined using automated perimetry with central 24-2 program. Optical coherent tomography (OCT) was done to assess the neuroretinal rim area, vertical cup/disc ratio, and average superior and inferior retinal nerve fiber layer thickness. PERG was recorded using skin electrodes. Amplitude and latency of P50 and N95 were documented. Results: PERG data: the mean P50 and N95 latency were significantly higher in the POAG group and the OHT group compared with the control group (P
Source: Journal of Glaucoma - Category: Opthalmology Tags: Original Studies Source Type: research