Microwave-assisted intramolecular reductive Heck in aqueous medium: Synthesis of 3,3′-Disubstituted heterocyclic compounds

Publication date: Available online 2 October 2019Source: Journal of Organometallic ChemistryAuthor(s): Karu Ramesh, Gedu SatyanarayanaAbstractHeterocyclic products have been accomplished using microwave-assisted [Pd]-catalyzed intramolecular reductive Heck coupling. The protocol found suitable in delivering indolines, oxindoles, and dihydrobenzofurans. Notably, the process was successful in sole aqueous medium and furnished the products bearing a quaternary carbon center.Graphical abstract

Source: Journal of Organometallic Chemistry - October 4, 2019 Category: Chemistry Source Type: research