IJERPH, Vol. 16, Pages 3747: Linking Geospatial and Laboratory Sciences to Define Mechanisms behind Landscape Level Drivers of Anthrax Outbreaks

Conclusions: Rainfall induced cycling of pH and calcium in soils plays a plausible role in amplifying spore load and persistence in endemic anthrax zones. Observed evidence of B. anthracis favoring soil alkalinity and high soil calcium levels in the environment were linked to physiological conditions that promote bacterial growth, survival, toxin secretion and spore formation; illustrating the utility of bringing laboratory-based (controlled) microbiology experiments into the fold of zoonotic disease ecology.
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research

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Journal of Neurotrauma, Ahead of Print.
Source: Journal of Neurotrauma - Category: Neurology Authors: Source Type: research
Publication date: Available online 9 December 2019Source: Materials LettersAuthor(s): Yulin Lin, Jianing Liu, Dong Bian, Zhiqiang Huang, Zefeng Lin, Ming Wang, Xiao Chu, Mei Li, Yu Zhang, Yufeng ZhengAbstractThe feasibility of Mg-1Sc alloy as orthopedic implant was studied by in vivo implantation into femur shaft of rabbit. The in vivo corrosion rate of Mg-1Sc alloy was 0.60 ± 0.06 mm·y-1. Mg-1Sc alloy could maintain its structural and mechanical integrity for more than 5 months. Compared with Ti6Al4V alloy, Mg-1Sc showed better osteogenesis. The corrosion products were mainly composed of Mg(OH)2, MgCO3&middo...
Source: Materials Letters - Category: Materials Science Source Type: research
In this study, prophylactic passive immunization was performed in a miniature swine model, using two vaccination-induced monoclonal antibodies (mAb), JEV-31 and JEV-169. These were selected as representatives for antibodies reactive with the major antigenic structures in the E protein of JEV and related flaviviruses. JEV-31 recognizes the lateral ridge of E protein domain III (EDIII) whilst JEV-169 has a broad footprint of binding involving residues throughout domains I (EDI) and II (EDII) of the E protein. Detection of neutralizing antibodies in the serum of immunized animals mimics the presence of neutralizing antibodies...
Source: Antiviral Therapy - Category: Virology Source Type: research
In this study, the thermodynamic database software Factsage7.0 was applied to study the influences of calcium, oxygen and sulfur contents on tin removal, and the equilibrium concentration of calcium-tin in molten steel was calculated. The results show that tin removal in molten steel should be under the reduction condition, and the critical calcium content increases with the improvement of the contents of oxygen and sulfur, however, it decreases with the increase of tin content. The lower temperature is helpful to tin removal. In addition, the oxygen content must be reduced firstly, and then the sulfur content should also ...
Source: Results in Physics - Category: Physics Source Type: research
Publication date: Available online 9 December 2019Source: Fish &Shellfish ImmunologyAuthor(s): Qingchao Wang, Wei Ji, Zhen XuAbstractIn the past decades, the aquaculture industry made great progress in China, which contributes more than 70% yield of the world's farmed fish. Along with the rapid growth of fish production, increased emergence and outbreak of numbers of diseases pose harm to the aquaculture industry and food safety. From the efficient, safe, environmental and ethical aspects, vaccines is definitely the most appropriate and focused method to control different kinds of fish diseases. In China, researchers h...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Recent occurrences of filoviruses and the arenavirus Lassa virus (LASV) in overlapping endemic areas of Africa highlight the need for a prophylactic vaccine that would confer protection against all of these viruses that cause lethal hemorrhagic fever (HF). We developed a quadrivalent formulation of VesiculoVax that contains recombinant vesicular stomatitis virus (rVSV) vectors expressing filovirus glycoproteins and that also contains a rVSV vector expressing the glycoprotein of a lineage IV strain of LASV. Cynomolgus macaques were vaccinated twice with the quadrivalent formulation, followed by challenge 28 days after the b...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Publication date: Available online 9 December 2019Source: Colloids and Surfaces B: BiointerfacesAuthor(s): Ting Lei, Wanqi Zhang, Hu Qian, Poon Nian Lim, Eng San Thian, Pengfei Lei, Yihe Hu, Zuyong WangAbstractBiomaterials composed of polymers and bioceramics have great prospects to repair large and complicated bone defects. Here, we developed a composite film consisting of poly(∑-caprolactone) (PCL) and silicon-substituted hydroxyapatite (Si-HA) nanoparticles to enhance the osteogenic effects of the scaffold for bone tissue engineering applications. The results showed that the Si-HA nanoparticles obtained an even dist...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
AbstractPurpose of reviewThis manuscript reviews the data on the mechanisms and significance of atherosclerotic cardiovascular disease (ASCVD) in masters athletes. It describes recent advances in understanding the biological pathway for the development and progression of ASCVD in athletes. It also reviews salient clinical trials, guidelines on managing ASCVD in masters athletes, and future research directions.Recent findingsRecent data have produced controversy as to whether high levels of physical activity and endurance training can promote ASCVD. Longstanding, vigorous endurance exercise may increase the development of c...
Source: Current Treatment Options in Cardiovascular Medicine - Category: Cardiology Source Type: research
This study also provides preliminary survey results regarding the population diversity ofB.anthracis in China, which will help promote the prevention and control of this important disease.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
James McGrane, FAO ECTAD Indonesia Team Leader, at his office in Jakarta. Credit: Kanis Dursin/IPSBy Kanis DursinJAKARTA, Indonesia, Jul 10 2017 (IPS)Poultry farmer Bambang Sutrisno Setiawan had long heard about biosecurity but never gave serious thought to it, even when the highly pathogenic avian influenza H5N1 forced him to cull thousands of his layer chickens in 2003 and 2009.Eighteen years into the business, however, Bambang, who is called Ilung by friends, is now converting his second farm into a three-zone biosecurity poultry with a strong conviction that it is the only way to save his business amid continued threat...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Asia-Pacific Economy & Trade Featured Food & Agriculture Headlines Health Projects avian flu biosafety Food and Agriculture Organization of the United Nations (FAO) Improving the lives of rural populations: better nutrition & agricultu Source Type: news
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