Newly approved devices for endovascular treatment of femoropopliteal disease: a review of clinical evidence.

Newly approved devices for endovascular treatment of femoropopliteal disease: a review of clinical evidence. Expert Rev Cardiovasc Ther. 2019 Oct 01;: Authors: Giannopoulos S, Armstrong EJ Abstract Introduction: Femoropopliteal lesions account for a significant proportion of endovascular interventions for peripheral artery disease. In this manuscript we review the literature on the application of newly approved devices in the treatment of atherosclerotic lesions at this segment. Areas covered: New drug-coating technologies provide sustained drug-eluting over time and better scaffolds are more resistant to the increased biomechanical stress at the femoropopliteal segment. Thus, the newer drug-eluting stents (i.e.Eluvia®), nitinol interwoven stents (i.e.Supera®), and drug-coated balloons (i.e.Stellarex®) are associated with improved pharmacokinetic profiles and promising primary patency rates. A major predictor of technical failure and restenosis is the calcification of the target vessel. Recently, intravascular lithotripsy of calcified lesions at the femoropopliteal segment with the Shockwave® balloon was introduced as a feasible treatment option for these complex lesions. Finally, we also describe the Tack Endovascular System®, the first-of-its-type, for the repair of post-angioplasty dissections. Expert opinion: The use of innovative stent designs and novel drug-coating, the application of adjunctive intravascular lithotripsy a...
Source: Expert Review of Cardiovascular Therapy - Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research