Awareness of breast cancer incidence and risk factors among healthy women in Germany: an update after 10 years

This study investigated changes in women’s risk factor awareness between 2004 and 2016. Results from a 2004 survey of 2107 healthy women were compared with new data obtained using the same questionnaire in 2016, with 866 participants indicating their knowledge and perceptions regarding breast cancer incidence, risk factors, risk perceptions, and levels of concern. Logistic regression models assessed the influence of time point (2004 vs. 2016) on correct recognition of risk factors such as age at first childbirth, childlessness, lack of breastfeeding, hormone replacement therapy (HRT), and family history. Regression models were adjusted for common sociodemographic characteristics. Reproductive risk factors were regarded as influencing breast cancer risk less often. In 2004, age at first birth, childlessness, and lack of breastfeeding were regarded as risk factors by 24, 32, and 37%, respectively, in comparison with only 15, 18, and 23% in 2016. All changes were statistically significant. Awareness of HRT as a risk factor increased significantly (36–57%), and family history was recognized as a risk by 75 and 73% in 2004 and 2016, respectively. Most women recognized family history as a breast cancer risk factor. This did not change, reflecting the topic’s media prominence. Awareness of HRT as a risk factor increased, probably owing to public information after the large HRT studies. It is unclear why reproductive risk factors are less frequently recognized; educ...
Source: European Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Research Papers: Breast Cancer Source Type: research

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Publication date: Available online 7 November 2019Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Meletios P. Nigdelis, Irene Lambrinoudaki, Dimitrios G. Goulis
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Abstract Hormone replacement therapy (HRT) remains the most effective treatment for menopausal symptoms and has been shown to prevent bone loss and fracture. The progestogen is added to provide endometrial protection in women with an intact uterus. After the publication of the initial WHI (Women's Health Initiative) results in 2002 reporting an overall increased risk of breast cancer, many women discontinued HRT. Despite the re-analysis of the results by subgroups of patients and updates with extended follow-up, much controversy remains, which we will analyze later in the text. Different types of estrogen or proge...
Source: Medicina (Kaunas) - Category: Universities & Medical Training Authors: Tags: Medicina (Kaunas) Source Type: research
New findings published in the Lancet medical journal say the risk of breast cancer associated with hormone replacement therapy is higher than previously thought, but doctors say women need to weigh the risk against the severity of menopause symptoms.
Source: CBC | Health - Category: Consumer Health News Tags: News/Health Source Type: news
Women who use hormone replacement therapy to treat symptoms of the menopause should be vigilant for signs of breast cancer, even after stopping HRT, the Medicines and Healthcare products Regulatory Agency has advised.
Source: The Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
A large, collaborative study, published in theLancet, reports that hormone replacement therapy increases the risk of breast cancer, long after patients stop taking it, and that more monitoring is required.Guardian
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
HORMONE replacement therapy causes an estimated 3,000 cases of breast cancer a year in the UK, scientists claimed yesterday. Almost all forms of the treatment were linked to an increase in cancer risk, a study revealed. The findings suggest women who use HRT to relieve symptoms of the menopause could increase their risk of breast cancer by twice as much as previously thought.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Study prompts medicines regulator to advise all women using HRT to remain vigilantThe risk of breast cancer from using hormone replacement therapy is double what was previously thought, according to a major piece of research, which confirms that HRT is a direct cause of the cancer.The findings of the definitive study will cause concern among the 1 million women in the UK and millions more around the world who are using HRT. It finds that the longer women take it, the greater their risk, with the possibility that just one year is risk-free. It also finds that the risk does not go away as soon as women stop taking it, as had...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Cancer research Menopause Medical research Drugs Ageing Science Breast cancer Health Society UK news Source Type: news
New data has confirmed that the risk of breast cancer is increased during use of all types of HRT, except vaginal oestrogens, and have also shown that an excess risk of breast cancer persists for long
Source: Royal Pharmaceutical Society News - Category: Drugs & Pharmacology Source Type: news
Women aged 50 to 69 who take the most common type of HRT for five years or more run a 32 per cent risk of developing breast cancer s Oxford research says the therapy causes one in 20 cases.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Publication date: 25 October 2019Source: Journal of Pharmaceutical and Biomedical Analysis, Volume 175Author(s): Csaba Ferenc Laszlo, Jonathan Paz Montoya, Marie Shamseddin, Fabio De Martino, Alexandre Beguin, Rene Nellen, Stephen James Bruce, Marc Moniatte, Hugues Henry, Cathrin BriskenAbstractIn the context of hormonal contraception and hormone replacement therapy (HRT), many women are exposed to exogenous hormones. Current use of hormonal contraception with combined ethinyl estradiol and different progestins bestows a breast cancer relative risk (RR) of 1.2- while combined HRT has a RR of 2. Although these exposures pre...
Source: Journal of Pharmaceutical and Biomedical Analysis - Category: Drugs & Pharmacology Source Type: research
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