Clinical, Endoscopic, and Histologic Findings at the Distal Esophagus and Stomach Before and Late (10.5 Years) After Laparoscopic Sleeve Gastrectomy: Results of a Prospective Study with 93% Follow-Up
ConclusionsPatients submitted to LSG showed a significant and progressive increase in the presence of “de novo” GERD. Also, an increased duodenogastric reflux was seen through an open and immobile pylorus. Therefore, based on these results, it seems like LSG is a “pro-reflux” surgical procedure, which should be continuously evaluated late after surgery.
ConclusionEE is more prevalent after SG compared with RYGB in a pre-bariatric surgery cohort with GERD. SG is associated with significant esophageal physiologic changes conducive to GERD and its clinical consequences.
Abstract Obesity is a global health epidemic with considerable economic burden. Surgical solutions have become increasingly popular following technical advances leading to sustained efficacy and reduced risk. Sleeve gastrectomy accounts for almost half of all bariatric surgeries worldwide but concerns regarding its relationship with gastroesophageal reflux disease (GERD) has been a topic of debate. GERD, including erosive esophagitis, is highly prevalent in the obese population. The role of pre-operative endoscopy in bariatric surgery has been controversial. Two schools of thought exist on the matter, one that bel...
Conclusions: The expression of MMP-9 is most common in severe forms compared to the mild forms of GRD. PMID: 31264989 [PubMed - in process]
This study investigated whether a reduction in the waist is associated with EE resolution.
Gastroesophageal reflux disease (GERD) is common in obese individuals. Prospective studies investigating validated GERD questionnaires and clinical parameters at identifying erosive esophagitis (EE) in this population are limited.
Conclusion: The VAT and the VAT/SAT ratio were significantly associated with the mucosal breaks in the LC of EGJ. Visceral obesity could influence the location of the mucosal breaks on EGJ. PMID: 30911296 [PubMed]
AbstractBackgroundRecent evidence has indicated an increased risk of Barrett ’s esophagus (BE) in the long term after sleeve gastrectomy (SG).AimThe aim of the study is to investigate the spectrum of gastroesophageal reflux disease (GERD) symptoms as well as the prevalence of BE, at minimum 5 years after SG in patients who underwent SG in different bariatric centers of two countries: France and Italy.Patients and MethodsFive high volume outpatient centers dedicated to bariatric surgery that routinely perform upper GI endoscopy before any bariatric procedures were invited to participate in the study. From Januar...
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-0783-2327 Introduction Gastroesophageal reflux disease (GERD) is more frequent in patients with diabetes mellitus (DM).The aim of the present study was to evaluate GER in asymptomatic patients with DM using 24-h pH impedance. Materials and Methods 19 healthy controls and 35 patients with DM without typical GERD symptoms were enrolled in the study. A 24-h pH-impedance study, esophageal manometry and gastroscopy were performed on all patients with DM. In the control group, an impedance study was performed on all subjects, and gastroscopy and esophageal manometry were performed on t...
Conclusions: EE resolution is associated with a decrease in BMI, and weight loss is potentially an effective GERD treatment. PMID: 30037170 [PubMed - as supplied by publisher]
Gastroesophageal reflux disease (GERD) and erosive esophagitis are common in patients with severe obesity and in people with type 2 diabetes mellitus (T2DM). Assessment of GERD is recommended before bariatric surgery because it may affect surgical method of choice. GerdQ is a validated questionnaire for diagnosis of GERD with sensitivity of 65% and specificity 71% in primary care patients consulting for upper GI complaints. Our aim was to assess the diagnostic accuracy of GerdQ in two groups of patients preparing for bariatric surgery, one group with and one without T2DM, respectively.